Impact of maedi-visna in intensively managed dairy sheep

Benavides, Julio; Fuertes, M.; García-Pariente, Carlos; Otaola, J. A.; Delgado, L.; Giráldez, Javier; Marı́n, Juan Francisco Garcı́a; Ferreras, M.C.; Pérez, Valentín Pérez

doi:10.1016/j.tvjl.2013.03.031

Cited by 26 publications

(24 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A survey performed in the United Kingdom has estimated that losses associated with Small Ruminant Lentivirus infections could be as high as 40% (Ritchie and Hosie, 2010). Further, in a study performed in intensively-managed dairy flocks in Spain, it has been concluded that moderate to severe pathological findings associated with the disease were present in 52% or 80% of animals that died or were culled, and which had affected the lungs, the brain and/or the mammary glands, thus highlighting this disease as a major cause of animal loss (Benavides et al, 2013).…”

Section: Significance In Adult Animalsmentioning

confidence: 99%

Significance of respiratory diseases in the health management of sheep

Lacasta

González

Navarro

et al. 2019

Small Ruminant Research

View full text Add to dashboard Cite

 Respiratory diseases of sheep produce a relevant economic impact in ovine industry.  In lambs, the principal adverse effects are related to mortality and poor quality of lambs produced.  In adults, financial losses are related to reduced production of affected sheep, need for early culling and death.  These are multi-faceted diseases and prevention is based on management practices.  Appropriate health measures that improve animal immune response also will help control of the diseases.

show abstract

Section: Significance In Adult Animalsmentioning

confidence: 99%

Significance of respiratory diseases in the health management of sheep

Lacasta

González

Navarro

et al. 2019

Small Ruminant Research

View full text Add to dashboard Cite

show abstract

“…Durante as coletas de sangue também realizou-se exame clínico da glândula mamária nas fêmeas através da inspeção e palpação, a fim de verificar alterações na consistência, na temperatura e alteração do linfonodo retromámario. Após a coleta, os tubos foram centrifugados em centrífuga (Excelsa ® II 206 BL) 2 não refrigerada a 1.500 g por 15 min, com o plasma e a camada de leucócitos transferidos separadamente para microtubos 3 , sendo a camada de leucócitos colocada juntamente com 600 μL de cloreto de amônia 4 , após todos os microtubos eram acondicionados em gelo em embalagem isotérmica (isopor), e encaminhados a Embrapa Caprinos e Ovinos em Sobral, Ceará, onde foram estocados a -20°C.…”

Section: Procedimento Experimentalunclassified

Comparison of Serological and Molecular Tests for Diagnosis of Caprine Arthritis Encephalitis and Clinical Evaluation of Mammary Glands of Infected Dairy Goats

Azevedo

Pinheiro

Santos

et al. 2019

Acta Scientiae. Vet.

View full text Add to dashboard Cite

Background: Caprine Arthritis Encephalitis (CAE) is a disease that causes productive losses in dairy goat flocks due to the reduction in milk production, followed by lesions in joints and mammary glands. An early diagnosis is essential, considering that there is frequent occurrence of asymptomatic animals. Hence, this study aimed to perform a comparison of immunological and molecular based diagnostic tests, represented by Agar Gel Immunodiffusion (AGID), Western Blot (WB) and nested Polymerase Chain Reaction (nPCR). In addition, the mammary glands (MG) of dairy goats were clinically evaluated. Material, Methods & Results: Blood collection and clinical examination were performed in 1191 dairy goats of 12 farms located in Northeastern and Southeastern regions of Brazil. Serological (AGID, WB) and molecular (nPCR) test results were compared and the data, along with MG alterations, were analyzed using Epi-info 7 and WinEpiscope 2.0. Seroprevalence in AGID test was 41.14% (490/1191). In WB, 51.47% (613/1191) of animals were seropositive and nPCR detected 69.44% (827/1191) positive animals. Hence, WB was more sensitive (P < 0.001) than AGID. However, nPCR detected more positive animals than AGID (P < 0.001) and WB (P < 0.001). The analysis of mammary glands revealed that 105 out of 1096 nanny goats presented alterations, of which 101 presented altered consistency, 16 presented elevated temperatures and 60 had enlarged retromammary lymph nodes. There was significant statistic difference (P < 0.05) only when comparing the results of serological tests with MG alterations.Discussion: In general, AGID technique is most frequently used when screening flocks for the disease due to the practicality and low cost this test presents. However, the results demonstrated that AGID detected the lowest number of positive animals. This low sensitivity that the test presented may be attributed to its antigen-antibody interaction mechanism, considering that agar gel precipitation requires multiple interactions. In addition, WB was more effective than AGID in detecting antibodies. On the other hand, nPCR was important for the detection of infected animals that serological tests failed to detect. The intermittence of immunological response observed in the serological tests may be explained by the variation of antibodies levels that may occur during life. Likewise, viral compartmentalization would justify the intermittent detection of proviral DNA. Hence, the results can be influenced by the viral intermittence, test sensitivity, late seroconversion and statistic values that can be calculated (sensitivity, specificity, positive predictive value, negative predictive level and kappa). Crossing the results of the diagnostic tests with the different mammary gland alterations, it was shown that there was a statistically significant difference (P <0.05) only in the comparison of the results of the serological tests with GM alterations. Everything indicates that the humoral or cellular immune system being on stimulus is more propitious to find these changes. In conclusion, WB was more sensitive than AGID and, considering that nPCR can detect a larger number of animals infected with the goat lentivirus, it must be associated with a sensible serological test, such as Western Blot. In addition, infected animals have alterations in MG, which is more frequent in cases with positive serological results.

show abstract

“…However, breed differences for pneumonia were not significant (p>0.05), these results being encouraging for the further introduction of the Dorper and White Dorper breeds to commercial flocks. No available data for comparison on pneumonia occurrence in European countries was found, except for information on flocks infected with Maedi-Visna (Benavides et al, 2013). …”

Section: Resultsmentioning

confidence: 99%

Reproduction Efficiency and Health Traits in Dorper, White Dorper, and Tsigai Sheep Breeds under Temperate European Conditions

Gavojdian

Budai

Cziszter

et al. 2015

Asian Australas. J. Anim. Sci

View full text Add to dashboard Cite

The objective of the current pilot study was to evaluate the reproductive performance and health indicators in Dorper, White Dorper, and Tsigai breed ewes managed semi-intensively under European temperate conditions. A total of 544 ewe-year units were observed, with ewes (ranging from 1.5 to 8 years of age) managed under identical rearing conditions for a period of two consecutive production cycles (2012 through 2013 and 2013 through 2014). In general, significant (p≤0.001) genotype-related disparities were found in occurrence rates for all health parameters taken into study. Clinical mastitis incidence was significantly lower (p≤0.05) in Dorper (9.4%) and White Dorper (10.8%) breeds compared to that of Tsigai ewes (17.4%). Significant differences (p≤0.05) for lameness were found between Dorper and Tsigai breeds, with occurrence rates of 8.0% and 2.9%, respectively. Incidence for pneumonia and abortion was not influenced (p>0.05) by the ewes’ genotype. Litter size was significantly lower (p≤0.05) in White Dorper breed than for Dorper and Tsigai ewes, of 1.21, 1.40, and 1.45, respectively. Conception rates and lambs survival were not affected (p>0.05) by genotype. Results suggest that South African Dorper and White Dorper sheep breeds have adapted well to the specific rearing conditions.

show abstract

Impact of maedi-visna in intensively managed dairy sheep

Cited by 26 publications

References 26 publications

Significance of respiratory diseases in the health management of sheep

Significance of respiratory diseases in the health management of sheep

Comparison of Serological and Molecular Tests for Diagnosis of Caprine Arthritis Encephalitis and Clinical Evaluation of Mammary Glands of Infected Dairy Goats

Reproduction Efficiency and Health Traits in Dorper, White Dorper, and Tsigai Sheep Breeds under Temperate European Conditions

Contact Info

Product

Resources

About