Impact of Local Adjuncts to Scaling and Root Planing in Periodontal Disease Therapy: A Systematic Review

Bonito, Arthur J.; Lux, Linda J; Lohr, Kathleen N

doi:10.1902/jop.2005.76.8.1227

Cited by 209 publications

(193 citation statements)

References 46 publications

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“…Another systematic review corroborated our findings and showed that the most positive results occurred for exactly these substances and that their local administration generally reduced PD levels significantly [73]. However, when compared to SRP alone, the benefit in this study seemed to be rather small (0.1-0.5 mm).…”

Section: Discussionsupporting

confidence: 86%

Improving Scaling And Root Planing Over The Past 40 Years: A Meta-Analysis

M¹

2014

Dentistry

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Aim: To screen whether or not classical non-surgical periodontal therapy improved over the last four decades and how adjunctive local or systemic measures influenced its clinical outcome. Methodology:Starting from the year 1970, the entire annual sets of publications of every 5th year of the "Journal of Clinical Periodontology" and the "Journal of Periodontology" were hand searched for articles dealing with nonsurgical periodontal therapy, i.e. scaling and root planing either alone (SRP) or in combination with adjunctive local (SRPloc) or systemic (SRPsyst) treatment. Mean pocket reduction was computed for each of the three treatment modalities. Where applicable, a meta-analysis and a meta-regression as well as linear regression were performed.Results: A total of 52 articles were found. Twenty-six thereof were randomized clinical trials. The meta-analysis revealed a standardized mean difference of pocket reduction of 0.77 mm (95% CI=0.283; 1.255) and 0.90 mm (95% CI 0.210; 1.593 for SRPloc-SRP and SRPsyst-SRP, respectively (P<0.0001). Meta regression showed significantly more mean pocket reduction for SRPloc (p=0.011) and SRPsyst (p=0.001) than for SRP. In addition, a negative correlation between time to re-evaluation and mean pocket reduction could be found (p=0.015). None of the treatment modalities improved over the past 40 years. Conclusion:Adjunctive local or systemic measures seem to improve the classic non-surgical periodontitis therapy, i.e. scaling and root planing. None of the three analyzed treatment modalities improved over the past 40 years.

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Section: Discussionsupporting

confidence: 86%

Improving Scaling And Root Planing Over The Past 40 Years: A Meta-Analysis

M¹

2014

Dentistry

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“…However, key questions facing periodontitis and general dentists is whether SRP accompanied by use of an adjunctive antimicrobial agent improves patient outcome over time more than SRP alone in chronic periodontitis cases [2]. Mechanical debridement alone may fail to remove pathogenic organisms because of their location in sub epithelial connective tissue and crevicular epithelial cells [3][4][5][6][7][8].…”

Section: Inrtoductionmentioning

confidence: 99%

“…In a systematic review conducted by Bonito Arthur J et al, [2], it was found that among the locally administered adjunctive antimicrobials the most positive results occurred from tetracycline, minocycline, metronidazole and chlorhexidine. Hyaluronic Acid (HA) is a recent addition to the local chemotherapeutic agents.…”

Section: Inrtoductionmentioning

confidence: 99%

Hyaluronic Acid as an Adjunct to Scaling and Root Planing in Chronic Periodontitis. A Randomized Clinical Trail

Padma

Baramappa

Rao

et al. 2014

JCDR

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Aim: Aim of the present study was to evaluate the adjunctive effect of local application of hyaluronon gel following scaling and root planing (SRP) in chronic periodontitis patients. Materials and Methods:In this randomized split mouth study 33 subjects with chronic periodontitis were evaluated after full mouth SRP. In the test sites hyaluronon gel was applied immediately after SRP and one week post therapy, the control sites were treated with SRP alone. Bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded at baseline, 4 wk and 12 wk.Results: Significant reduction in BOP scores was observed in both the groups at 12weeks (p<0.001). The hyaluronon group

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“…Overall efficacy of local antibiotic therapies has been evaluated using meta-analysis of fifty articles, each reporting studies of at least six months follow-up (Bonito, et al, 2005). The meta-analysis considered studies of the addition of local adjuncts and found such additions provide generally favorable but minimal differences.…”

Section: Antimicrobialmentioning

confidence: 99%

Present and Future Non-Surgical Therapeutic Strategies for the Management of Periodontal Diseases

Leite¹,

Kirkwood²

2012

Periodontal Diseases - A Clinician's Guide

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Impact of Local Adjuncts to Scaling and Root Planing in Periodontal Disease Therapy: A Systematic Review

Abstract: Whether such improvements, even if statistically significant, are clinically meaningful remains a question. A substantial agenda of future research to address this and other issues (e.g., costs, patient-oriented outcomes) is suggested.

Cited by 209 publications

References 46 publications

Improving Scaling And Root Planing Over The Past 40 Years: A Meta-Analysis

Improving Scaling And Root Planing Over The Past 40 Years: A Meta-Analysis

Hyaluronic Acid as an Adjunct to Scaling and Root Planing in Chronic Periodontitis. A Randomized Clinical Trail

Present and Future Non-Surgical Therapeutic Strategies for the Management of Periodontal Diseases

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