Impact of Kangaroo Mother Care on Skin Microbiome of Very Preterm Infants - A Pilot Study

Govindarajan, Varun; Devadas, Sahana; Shah, Pritik A; Diggikar, Shivashankar

doi:10.1007/s12098-023-04562-4

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…Moreover, the physical contact involved in kangaroo care facilitates the transmission of maternal skin microbiota to the infant skin microbiome. This exposes the infant to a wide range of microbial species that play a crucial role in immune system development [ 148 ]. In addition, kangaroo care has also been associated with improved gut maturation in premature infants with underdeveloped digestive systems [ 149 ].…”

Section: Future Perspectives and Therapeutic Potentialmentioning

confidence: 99%

The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect

Dias,

Pheiffer,

Adam

2023

Microorganisms

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Gestational diabetes mellitus (GDM) is a growing public health concern that affects many pregnancies globally. The condition is associated with adverse maternal and neonatal outcomes including gestational hypertension, preeclampsia, placental abruption, preterm birth, stillbirth, and fetal growth restriction. In the long-term, mothers and children have an increased risk of developing metabolic diseases such as type 2 diabetes and cardiovascular disease. Accumulating evidence suggest that alterations in the maternal microbiome may play a role in the pathogenesis of GDM and adverse pregnancy outcomes. This review describes changes in the maternal microbiome during the physiological adaptations of pregnancy, GDM and adverse maternal and neonatal outcomes. Findings from this review highlight the importance of understanding the link between the maternal microbiome and GDM. Furthermore, new therapeutic approaches to prevent or better manage GDM are discussed. Further research and clinical trials are necessary to fully realize the therapeutic potential of the maternal microbiome and translate these findings into clinical practice.

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Section: Future Perspectives and Therapeutic Potentialmentioning

confidence: 99%

The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect

Dias,

Pheiffer,

Adam

2023

Microorganisms

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“…Firstly, KMC is associated with increased rates of successful breastfeeding 118 and reduced time to initiation of breastfeeding, 119 which can help to repair the microbiota after antibiotics as discussed above. Secondly, skin-to-skin contact is also associated with changes to the microbiota including a lower prevalence of organisms associated with gut dysfunction and other pathogenic species, 120 which may relate to the stress reduction and successful breastfeeding associated with skin-to-skin contact. 121 However, much of the research regarding the benefits of KMC focuses on preterm infants, and term babies are also at risk of neonatal sepsis, particularly in the resource-limited setting.…”

Section: Family-integrated Carementioning

confidence: 99%

“…Further research into changes in the microbiota and its associations with disease is required in order to make firm recommendations. 120 Finally, although contact with the mother seems preferable for infection control to handling by multiple healthcare workers or incubator sharing in resource-limited settings, particularly where neonatal wards may be crowded, further study is needed to ensure that skin-to-skin contact does not expose vulnerable neonates to pathogenic organisms.…”

Section: Family-integrated Carementioning

confidence: 99%

Improving the Treatment of Neonatal Sepsis in Resource-Limited Settings: Gaps and Recommendations

Sturrock,

Sadoo,

Nanyunja

et al. 2023

RRTM

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Neonatal sepsis causes significant global morbidity and mortality, with the highest burden in resource-limited settings where 99% of neonatal deaths occur. There are multiple challenges to achieving successful treatment of neonates in this setting. Firstly, reliable and low-cost strategies for risk identification are urgently needed to facilitate treatment as early as possible. Improved laboratory capacity to allow identification of causative organisms would support antimicrobial stewardship. Antibiotic treatment is still hampered by availability, but also increasingly by antimicrobial resistance – making surveillance of organisms and judicious antibiotic use a priority. Finally, supportive care is key in the management of the neonate with sepsis and has been underrecognized as a priority in resource-limited settings. This includes fluid balance and nutritional support in the acute phase, and follow-up care in order to mitigate complications and optimise long-term outcomes. There is much more work to be done in identifying the holistic needs of neonates and their families to provide effective family-integrated interventions and complete the package of neonatal sepsis management in resource-limited settings.

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Kangaroo Mother Care and Neonatal Skin Microbiome

Chawla

2023

Indian J Pediatr

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Impact of Kangaroo Mother Care on Skin Microbiome of Very Preterm Infants - A Pilot Study

Cited by 4 publications

References 20 publications

The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect

The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect

Improving the Treatment of Neonatal Sepsis in Resource-Limited Settings: Gaps and Recommendations

Kangaroo Mother Care and Neonatal Skin Microbiome

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