Abstract:BackgroundAlthough respiratory pathology is known to develop in young children with cystic fibrosis (CF), the determinants of early‐onset lung disease have not been elucidated.ObjectiveWe aimed to determine the impact of potential intrinsic and extrinsic risk factors during the first 3 years of life, testing the hypothesis that both contribute significantly to early‐onset CF lung disease.DesignWe studied 104 infants born during 2012–2017, diagnosed through newborn screening by age 3 months, and evaluated compr… Show more
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