Impact of Intraspinal Nerve Block Anesthesia on Intrapartum Fever and the Neonate

Abstract

Objective. To evaluate the impact of intraspinal nerve block anesthesia on intrapartum fever and the neonate. Methods. In this prospective study, between October 2019 and December 2020, 90 eligible primiparous women enrolled in the obstetrics and gynecology department of our hospital for delivery were recruited and assigned via the random number table method at a ratio of 1 : 1 to either an analgesic group given intraspinal nerve block anesthesia for labor or a nonanalgesic group without anesthesia for labor. Outcome measures included intrapartum body temperature, cases of intrapartum fever, Apgar scores of neonates, visual analogue scale (VAS) scores, delivery mode, and indomethacin use. Results. Intraspinal nerve block anesthesia was associated with a higher body temperature at 4 h and 5 h after analgesia and more cases of intrapartum fever versus no anesthesia ( P < 0.05 ). There were no significant differences in the Apgar scores between the two groups ( P > 0.05 ). Participants given intraspinal nerve block anesthesia had lower VAS scores during labor versus those without anesthesia ( P < 0.05 ). The differences in the delivery mode between the two groups were not significant ( P > 0.05 ). Intraspinal nerve block anesthesia resulted in a significantly higher demand for indomethacin versus no anesthesia ( P < 0.05 ). Conclusion. Intraspinal nerve block anesthesia is clinically effective in labor analgesia but may cause increased body temperature or even overt clinical fever, so close clinical observation of maternal temperature changes is required to mitigate the effects of anesthesia on the mothers. No adverse consequences of intraspinal nerve block anesthesia on the newborns were reported in this study.

Butorphanol Nasal Spray Relieves Pain and Distress in Women Under Epidural Labor Analgesia: A Randomized Controlled Trial

“…Studies have also found that butorphanol can pass through the blood-brain and placental barriers and enter human milk [18]. Other researchers have observed that intravenous administration of conventional doses of butorphanol had no signi cant effect on neonates [19,20]. These studies have shown that butorphanol is safe for intravenous use, and the butorphanol nasal spray used in our study has a satisfactory analgesic effect, with a rapid onset of nasal administration, maintenance time of up to 4-5 hours, and low incidence of adverse reactions.…”

Retracted: Impact of Intraspinal Nerve Block Anesthesia on Intrapartum Fever and the Neonate

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”