INTRODUCTIONIn a developing country like ours, which is the diabetic capital of the world, Polycystic ovary syndrome (PCOS) is one of the top listed endocrine disorders in women between 13 to 40 years of reproductive age.1 Prevalence of the disease is between 5 to 10%.2 Stein and Levinthal was the first to describe the condition.3 Rotterdam ESHRE/ASRM in the year 2003 standardized the definition of PCOS, which is characterized by a combination of oligomenorrhea / amenorrhea, clinical or endocrine signs of hyperandrogenemia and polycystic ovaries.
470% of the women suffer from normogonadotrophic anovulation, but with the presence of the ultrasound or endocrine features of PCOS.5 More than 50% of women diagnosed with PCOS are overweight or obese.6 This metabolic disorder is most commonly associated with infertility. 15-20% of the ABSTRACT Background: Polycystic ovarian syndrome (PCOS) in the present generation is a very common reproductive disorder and the prevalence is on the rise. It is associated with typical features such as insulin resistance, hyperandrogenemia and obesity which has deep implications on the pregnancy outcomes as well as a long-term health of the woman. Methods: Prospective comparative study performed over 200 pregnant women in the ESIC medical college, Bangalore. 100 women diagnosed with PCOS were compared with that of 100 normal women. The method of conception in pcos was recorded. maternal outcome in the form of abortion, gestational diabetes mellitus, hypertensive disorder in pregnancy, mode of delivery, intrapartum and postpartum complication. Fetal outcome in the form preterm delivery, small-for-gestational-age (SGA) infants, large-for-gestational-age infants, apgar at 5 minute and admission to NICU. Results: Of the 100 women who were diagnosed with PCOS, 62 had spontaneous conception, 32 conceived with ovulation induction, 4 with artificial insemination and 2 needed IVF for conception. 18 women had spontaneous abortion, 58 were diagnosed with Gestational diabetes mellitus (GDM) predominantly between 24 -28 weeks' period of gestation, 16 women had hypertension complicating pregnancy. Fetal outcome in the form of preterm birth was noted in 14 patients, large for gestation was noted in 11 newborns, the rate of NICU admission was significantly higher in the PCOS women's infants constituting 33%. Conclusions: The assistance needed for conception was significantly higher in women with PCOS. The complications associated with pregnancy such as spontaneous abortions, gestational diabetes, hypertensive disorder in pregnancy, preterm births, need of NICU care for the infants are much higher in women with PCOS. Adult health education and the preconception diagnosis and appropriate management of PCOS is an important primary mode of prevention of these associated complications.