Impact of in vitro gastrointestinal digestion on the bioaccessibility and antioxidant capacity of bioactive compounds from Passion fruit (Passiflora edulis) leaves and juice extracts

Abstract

The fruits consumption is highly associated with a lessening in the risk of the chronic noncommunicable diseases. Despite their content of bioactive compounds, physiological conditions might affect their bioaccessibility and biological potential. Hence, the purpose of this research was to evaluate the bioaccessibility and in vitro antioxidant capacity of bioactive compounds (polyphenols, ascorbic acid, and mono/oligosaccharides) from passion fruit (Passiflora edulis) juice and leaves extracts (PJE and PLE, respectively) during an in vitro gastrointestinal digestion. PLE exhibited the highest overall bioaccessibility of phenolics and mono/oligosaccharides. Ascorbic acid and kaempferol were the most bioaccessible (up to 12‐ and 13‐fold, respectively) compounds and showed the highest net permeabilities (0.32–34.65 × 10–5). Chlorogenic acid, quercetin, and xylose showed the highest correlation with the antioxidant capacity (ABTS/DPPH methods). These results indicated the ability of digestion to improve bioaccessibility and antioxidant capacity of bioactives compounds from P. edulis extracts. Practical applications Several international organizations, World Health Organization (WHO) among them, are actively encouraging an increase in the fruit and vegetable intake worldwide in response to the global rise in noncommunicable diseases, among other actions. Fruits and processed foods are increasingly used in the European food industry. Additionally, exotic and tropical fruits cannot be produced in the European Union, which opens up a variety of opportunities for our Colombian tropical fruits such as mango or exotic fruits such as passion fruit. Evaluating parameters such as bioaccessibility and intestinal permeability of these bioactives derived from both P. edulis juice and leaves extracts contributes with new evidence regarding their stability along the gastrointestinal tract and their consumption as a source of health‐promoting compounds. The results of this research are an important achievement on the way to make the transition from basic to applied research. Informing the health benefits of this tropical fruit can stimulate its demand.

New Advances in the Determination of Free and Bound Phenolic Compounds of Banana Passion Fruit Pulp (Passiflora tripartita, var. Mollissima (Kunth) L.H. Bailey) and Their In Vitro Antioxidant and Hypoglycemic Capacities

“…Recently, leaves, pulp, seeds and edible parts of banana passion fruit have been investigated regarding their composition, especially their phytochemical content [11][12][13]. Previous studies demonstrated that banana passion fruit is particularly rich in phenolic antioxidants [14,15]. Contreras-Calderón et al [16] found that banana passion fruits had the highest levels of antioxidant activity compared to other fruits, and this fact has been attributed to the presence of high amounts of phenolic compounds [12,13].…”

“…In the last few decades, their popularity has increased around the world, especially in developed countries, because they are associated with health promoting compounds [ 1 , 2 , 3 ]. Several investigations carried out in the last few years have highlighted the fact that these fruits are important sources of antioxidants such as phenolic compounds, vitamins, carotenoids and minerals [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ]. Their high phytochemical content contributes to their preventive effect against chronic degenerative diseases.…”

High‐intensity ultrasound processed acerola juice containing oligosaccharides and dextran promotes Lacticaseibacillus casei NRRL B‐442 growth

“…The final relative concentrations were 111%, 130%, 107%, 156%, and 123% for juices 1, 2, 3, 4, and 5, respectively. Digestive enzymes' activity can be responsible for the increase in ascorbic acid and phenolic compounds (Aguillón‐Osma et al ., 2019).…”

P. edulis Extract Protects Against Amyloid-β Toxicity in Alzheimer’s Disease Models Through Maintenance of Mitochondrial Homeostasis via the FOXO3/DAF-16 Pathway

“…Passi ora edulis (P. edulis), commonly known as passion fruit, is natively to the Southern American, but widely cultivated in tropical and subtropical areas worldwide. The pulp and pericarp of the passion fruit are a source of phytochemical contents such as polyphenols, triterpenoids, glycosides, carotenoids, polysaccharides, aromatic oils, and essential nutrients [14][15][16][17][18]. Pharmacological studies have identi ed the bioactivities of passion fruit including anti-oxidative, anti-in ammatory, anti-diabetic, and potentially hepatoprotective effects [19][20][21][22][23].…”