Impact of Hyponatremia on Morbidity, Mortality, and Complications After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review

Mapa, Ben; Taylor, Brittany L.; Appelboom, Geoffrey; Bruce, Eliza; Claassen, Jan; Connolly, E. Sander

doi:10.1016/j.wneu.2015.08.054

Cited by 69 publications

(52 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ayrıca yoğun bakımda kullanılan kristalloid solüsyonların ve radyolojik tetkikler için kullanılan radyoopak ilaçların da kanda sodyum ve potasyum dengesizliği yaptığı gösterilmiştir 27 . Diğer yandan serebral tuz kaybında ANP artışı olduğu ve bunun da böbrek tuz atılımını artırarak hiponatremiye neden olup özellikle SAK sonrası vazospazma gidişi hızlandırdığı rapor edilmiştir 12 . İlave olarak bu hastalarda hipotalamik disfonksiyon sonrası da hiponatremi/hipernatremi görülebileceği vurgulanmıştır 28 .…”

Section: Discussionunclassified

See 1 more Smart Citation

İntrakranial kanamaların prognozunda biyokimyasal belirteçler

Yüksel¹,

Öğden²,

Akkurt³

et al. 2018

Cukurova Medical Journal

View full text Add to dashboard Cite

The aim of this study was to determine prognosis of patients with intracranial hemorrhage by examining routine laboratory findings. Materials and Methods: Patients were divided into three groups according to hemorrhage type (subarachnoid hemorrhage, spontaneous intracerebral hematoma, subdural hematoma). Then serum sodium, potassium, Creactive protein, blood leukocyte count and neutrophil percentage values were measured pre-and postoperatively. Results: Twenty-eight patients (10 female, 18 male) were included in study. There was no difference among groups in terms of all parameters. However, postoperative leukocyte counts were higher than preoperative values in intracerebral hematoma group; and postoperative sodium levels were higher than preoperative values in subarachnoid hemorrhage group. There was found negative correlation between Glasgow Outcome Scale scores and preoperative neutrophil, preoperative and postoperative sodium values in subarachnoid hemorrhage group. A negative correlation was found between Glasgow Outcome Scale scores and preoperative C-reactive protein values in subdural hematoma group. Conclusion: Study results suggested that pre-and postoperative serum sodium values in subarachnoid hemorrhage; age, Glasgow Coma Scale score, pre-and post-operative C-reactive protein values in spontaneous intracerebral hematoma; and preoperative C-reactive protein values in subdural hematoma were considered to be predictors of patient prognosis.

show abstract

Section: Discussionunclassified

“…Renal fonksiyon bozukluklarının (kreatinin yüksekliği) intrakranial kanamalarda bağımsız belirteç olduğu savunulmaktadır 11,12,13 . Kan lökosit düzey yüksekliğinin subaraknoid kanamada belirgin prognostik belirteç olduğu savunulmuştur.…”

Section: Introductionunclassified

İntrakranial kanamaların prognozunda biyokimyasal belirteçler

Yüksel¹,

Öğden²,

Akkurt³

et al. 2018

Cukurova Medical Journal

View full text Add to dashboard Cite

show abstract

“…In general, rebleeding causes much more severe clinical manifestations than the initial bleeding and is associated with very high mortality. Its prevention is obtained by reducing the map and treatment of the aneurysm (surgical clipping or endovascular embolization), which justifies the earliest possible therapeutic approach (Zhao & Wei, 2017, Mapa et al, 2016.…”

Section: Recurrencementioning

confidence: 99%

Spontaneous Subarachnoid Hemorrhage: updated clinical and therapeutic approach

Pinheiro¹,

Ernesto²,

Rêgo³

et al. 2019

JPCBS

View full text Add to dashboard Cite

Despite advances in the treatment of subarachnoid hemorrhage, morbimortality rates remain elevated. Patients who have a sudden onset headache followed or not by altered consciousness, require a high degree of suspicion for the appropriate diagnosis in the emergency room. Those with lighter symptoms, presence of headache without other neurological alterations are the most susceptible to diagnostic error. All should be evaluated quickly, receiving specialized neurointensive care and ear

show abstract

“…If there is a low serum sodium level, cells will begin to swell as fluid moves from the extracellular compartment to the interstitial fluid, resulting in intracellular oedema due to changes in osmolarity. When hyponatraemia develops rapidly the brain can be slow to adapt to the hypotonic environment (Mapa et al, 2016;Spasovski et al, 2014;Verbalis et al, 2013). When low serum sodium levels are over corrected too rapidly it can cause blood brain barrier breakdown and injury to myelin in the central nervous system, precipitating osmotic demyelination syndrome (Ball & Iqbal, 2015;Sterns, Hix & Silver, 2010;Verbalis et al,.…”

Section: Pathophysiology Of Sah and Hyponatraemiamentioning

confidence: 99%

“…It is defined by Hickey (2014, p. 203) as 'serum sodium less than 135mEq/L'. High-grade SAH patients with anterior circulation aneurysms have a 50% incident rate of developing acute hyponatraemia (De Oliveira Manoel et al, 2016), yet the pathophysiology linking SAH and hyponatraemia is not fully understood (De Oliveira Manoel et al, 2016;Manzanares, Aramendi, Langlois & Biestro, 2014;Mapa et al, 2016;See, Wu, Lai, Gross, & Du, 2016).…”

Section: Introductionmentioning

confidence: 99%

Treatment of subarachnoid haemorrhage complicated by hyponatraemia

Butler

2017

Australasian Journal of Neuroscience

View full text Add to dashboard Cite

Abstract:Background statement: Developing hyponatraemia after a subarachnoid haemorrhage is common, however it is known to worsen patient outcomes. This paper aims to review the practice of managing hyponatraemia in acute subarachnoid haemorrhage patients with administration of 3% hypertonic saline solution.Aim: To enquire into the practice and policy of one of Melbourne's large Metropolitan hospital's current management of hyponatraemia in subarachnoid haemorrhage patients, and determine if the policy is both current and evidenced based.Methods: A search of the terms "subarachnoid haemorrhage", "hyponatraemia" and "hypertonic saline" was used in databases including Pubmed, Medline and CINAHL. Literature was included if it discussed the use of hypertonic saline for hyponatraemia, the effect of hyponatraemia on subarachnoid haemorrhage patients and the potential causes of acute hyponatraemia. The articles and literature reviews were assessed for inclusion by the author. Results:Patients with a subarachnoid haemorrhage and hyponatraemia should not be fluid restricted, as this is contraindicated. Patients should be administered 3% hypertonic saline to avoid hypovolaemia and slowly increase serum sodium to prevent onset or exacerbation of cerebral oedema.Limitation: Lack of evidence based data and studies in regard to the dosing of hypertonic saline resulted in the lack of consensus with prescribing rates and volumes to be infused for severe hyponatraemia.

show abstract

Impact of Hyponatremia on Morbidity, Mortality, and Complications After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review

Cited by 69 publications

References 52 publications

İntrakranial kanamaların prognozunda biyokimyasal belirteçler

İntrakranial kanamaların prognozunda biyokimyasal belirteçler

Spontaneous Subarachnoid Hemorrhage: updated clinical and therapeutic approach

Treatment of subarachnoid haemorrhage complicated by hyponatraemia

Contact Info

Product

Resources

About