Impact of hospitalization for vaso‐occlusive crisis on health‐related quality of life in children with sickle cell disease
Caroline Vuong,
Ibtissame Moussa,
Maud M. van Muilekom
et al.
Abstract:BackgroundSickle cell disease (SCD) is characterized by vaso‐occlusive crises (VOCs) that impair the health‐related quality of life (HRQoL). The aim of this study is to evaluate the impact of hospitalization for VOCs on HRQoL in children with SCD over time.MethodsIn this longitudinal cohort study, children aged 8–18 years diagnosed with SCD at the Amsterdam UMC were included between 2012 and 2021. HRQoL was annually measured as part of standard care using the Pediatric Quality of Life Inventory. The impact of … Show more
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