Impact of Hiv Infection on the Outcomes of Hospitalized Patients With Acute Decompensated Heart Failure: Analysis of National Inpatient Sample

Almani, Muhammad Usman; Usman, Muhammad; Kang, Cyra-Yoonsun; Akuna, Emmanuel; Asemota, Iriagbonse; Elbermawy, Mahmoud; Soon-Shiong, Raquel; Williams, Dimeji; Khanal, Smriti; Sharma, Bharosa; Stroger, John H.

doi:10.1016/s0735-1097(21)02209-9

Cited by 2 publications

(3 citation statements)

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“…Fifteen studies that met the quality appraisal are included in the systematic review, as discussed in Table 1 [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28].…”

Section: Resultsmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

“…In contrast, an observational study by Almani et al found that 975 of the 179,325 patients with acute decompensated HF (ADHF) were HIV-positive [ 27 ]. There was a 0.84 (95% CI 0.018 - 1.029, p=0.053) adjusted odds ratio for inpatient mortality in those with ADHF with HIV compared to those without HIV [ 27 ]. The inpatient mortality rates for HIV-infected patients admitted for ADHF were similar to those for HIV-negative patients, and they are more likely to develop infectious complications.…”

Section: Reviewmentioning

confidence: 99%

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A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases

Alzubaidee¹,

Dwarampudi²,

Mathew³

et al. 2022

Cureus

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Human immunodeficiency virus (HIV) primarily affects the immune systems, which, if progressed, will lead to acquired immunodeficiency syndrome (AIDS). Currently, there is no effective cure for the disease, and patients are affected lifelong, but there are antiretroviral medications that can control the disease's symptoms and progression. In addition, taking precautions during sexual contact, especially in the male homosexual population, while handling the patient's bodily fluids such as blood and saliva, and during childbirth by an infected mother is necessary to prevent the transmission of the virus. We used 15 studies, including systematic reviews and meta-analyses, observation studies, randomized clinical trials, and comprehensive reviews, to determine how HIV interferes with heart disease, increasing morbidity and mortality. We have used specific inclusion and exclusion criteria, focusing on specified age groups within a particular timeline. Some of the included studies found that many side effects from antiretroviral drugs can impact heart conditions, along with HIV, while others did not show a strong correlation between HIV and some heart diseases. In conclusion, after reviewing the literature, the results are inconclusive. More extensive trials focusing on the impact HIV has on heart disease are required to establish a strong correlation between HIV and heart disease to prevent morbidity and mortality.

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“…Fifteen studies that met the quality appraisal are included in the systematic review, as discussed in Table 1 [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28].…”

Section: Resultsmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

See 1 more Smart Citation

A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases

Alzubaidee¹,

Dwarampudi²,

Mathew³

et al. 2022

Cureus

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The Impact of Concomitant Diagnosis of Viral Infections on In-Hospital Mortality in Patients Hospitalized with a Diagnosis of Heart Failure in the United States: Insights from the National Inpatient Sample

Kwok

Abbas

Qureshi

et al. 2022

Viruses

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The impact of viral infections on patients admitted with a diagnosis of heart failure is not well understood. We conducted a retrospective cohort study using data from the National Inpatient Sample in the United States to evaluate the proportion of admissions with a diagnosis of heart failure and viral infections, and we explored how viral infections had impact on in-hospital mortality and length of stay. There were a total of 20,713,539 admission records with a diagnosis of heart failure included in the analysis and 3.8% had a concomitant diagnosis of viral infection. The mean length of stay was 20.1 ± 26.9 days, 12.9 ± 13.6 days, 12.1 ± 13.8 days, and 5.1 ± 6.5 days for records with a diagnosis of cytomegalovirus, viral meningitis/encephalitis, herpes simplex infection, and no viral infection, respectively. The most common diagnoses of viral infections were influenza (n = 240,260) and chronic viral hepatitis (n = 194,400), and the highest rates of mortality were observed for records with a diagnosis of cytomegalovirus (13.2%), acute viral hepatitis (12.5%), and viral meningitis/encephalitis (11.1%). The viral infections significantly associated with increased odds of mortality were cytomegalovirus infection (OR 1.84 95% CI 1.57–2.16), acute hepatitis (OR 1.29 95% CI 1.15–1.45), and HIV (OR 1.22 95% CI 1.11–1.34). In conclusion, viral infections are co-diagnosis in 3.8% of patient records with heart failure and detection of some viruses may be important as they increase mortality and may prolong length of stay in hospital.

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Impact of Hiv Infection on the Outcomes of Hospitalized Patients With Acute Decompensated Heart Failure: Analysis of National Inpatient Sample

Cited by 2 publications

References 0 publications

A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases

A Systematic Review Exploring the Effect of Human Immunodeficiency Virus on Cardiac Diseases

The Impact of Concomitant Diagnosis of Viral Infections on In-Hospital Mortality in Patients Hospitalized with a Diagnosis of Heart Failure in the United States: Insights from the National Inpatient Sample

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