Impact of gestational diabetes diagnosis on concurrent depression in pregnancy

Miller, Nathaniel E.; Curry, Elizabeth; Laabs, Susan; Manhas, Manisha; Angstman, Kurt B.

doi:10.1080/0167482x.2019.1709816

Cited by 10 publications

(13 citation statements)

References 9 publications

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“…A total sample of 71,036 pregnant women were included in the analyses. Among the 10 studies, six studies were conducted in USA [15,18,20,22], two studies were conducted in Australia [16,26], and one study conducted each in Brazil [11], Canada [24], Greece [27] and Ireland [17], respectively.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Other screening tools such as the Depression Anxiety Stress Scale [17], Mental Health Inventory Form [16], and Primary care evaluation of Mental disorders [11] were used in some of the studies. For diagnostic purposes, the International Classification of Disease [20,24] and Patient Health Questionnaire [22] were used. There were also studies [15] in which the screening tool for depression was not mentioned.…”

Section: Poormentioning

confidence: 99%

“…The mean age range was within 29 to 30.2 years old, however these values merely came from two studies that reported this value [11,26], and majority of the studies did not report mean age of respondent. In regard to quality of studies, the majority of studies had a score of 14 or above [15][16][17][18]20,22,24] except for three studies [11,26,27].…”

Section: Poormentioning

confidence: 99%

“…The funnel plot, Egger's test (p = 0.882) and Begg's test (p = 0.621) suggested that there was no publication bias ( Figure S1 and Table S3). Nevertheless, sensitivity analysis identified all studies had substantial influences on the overall relative risk, which cause variation in pooled RRs ranging from 1.313 to 1.605 [16][17][18]20,22,24,26,27].…”

Section: Dip and Risk Of Antepartum Depressionmentioning

confidence: 99%

“…However, diabetes in pregnancy (DIP) was not included in that systematic review. In fact, there has been literature reporting data on the occurrence of antepartum depression among women with and without DIP [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. Furthermore, DIP could be associated with the onset of antepartum depression.…”

Section: Introductionmentioning

confidence: 99%

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Diabetes in Pregnancy and Risk of Antepartum Depression: A Systematic Review and Meta-Analysis of Cohort Studies

Lee

Ching

Chong

et al. 2020

IJERPH

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Previous literature has reported that patients with diabetes in pregnancy (DIP) are at risk of developing antepartum depression but the results have been inconsistent in cohort studies. We conducted a systematic review and performed a meta-analysis to quantify the association between DIP and risk of antepartum depression in cohort studies. Medline, Cinahl, and PubMed databases were searched for studies investigating DIP involving pregnant women with pre-existing diabetes and gestational diabetes mellitus and their risk of antepartum depression that were published in journals from inception to 27 December 2019. We derived the summary estimates using a random-effects model and reported the findings as pooled relative risks (RR) and confidence interval (CI). Publication bias was assessed using a funnel plot and was quantified by Egger and Begg’s tests. Ten studies, involving 71,036 pregnant women were included in this meta-analysis. The pooled RR to develop antepartum depression was (RR = 1.430, 95% CI: 1.251–1.636) among women with gestational diabetes mellitus. Combining pregnant women with pre-existing diabetes mellitus and gestational diabetes mellitus, they had a significant increased risk of developing antepartum depression (RR = 1.431, 95% CI: 1.205–1.699) compared with those without it. In comparison, we found no association between pre-existing diabetes mellitus in pregnancy (RR = 1.300, 95% CI: 0.736–2.297) and the risk of developing antepartum depression. This study has a few limitations: first, different questionnaire and cut-off points were used in evaluation of depression across the studies. Second, there was a lack of data on history of depression prior to pregnancy, which lead to confounding bias that could not be solved by this meta-analysis. Third, data were dominated by studies in Western countries; this is due to the studies from Eastern countries failing to meet our inclusion criteria for statistical analysis. Women with gestational diabetes mellitus have an increased risk of developing antepartum depression compared to those without the disease. Therefore, more attention on the mental health status should be given on pregnant women diagnosed with pre-existing diabetes mellitus and gestational diabetes mellitus.

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