Impact of gender and mutational differences in hormone receptor expressing non-small cell lung cancer
Robert Hsu,
Denaly Chen,
Bing Xia
et al.
Abstract:BackgroundThe incidence of lung cancer in the US has been decreasing but a bigger decline has been observed in men despite similar declines in tobacco use between men and women. Multiple theories have been proposed, including exposure to exogenous estrogens. Our study seeks to understand the relationship between hormone receptors (HR), gender, and the genomic landscape of non-small lung cancer (NSCLC).Methods3,256 NSCLC tumor samples submitted for molecular profiling between 2013-2018 were retrospectively iden… Show more
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