Impact of gastrectomy for incurable advanced gastric cancer in urgent situations in the elderly

Fujimoto, Goshi; Kusanagi, Hiroshi; Hayashi, Ken; Miyazaki, Akira; Honjo, Hirotaka; Nakagi, Masafumi

doi:10.1016/j.asjsur.2022.06.001

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…În al treilea rând a existat un bias în ceea ce privește selecția pacienților, fiind incluși în studiu doar pacienții care s-au prezentat în urgență și au beneficiat de rezecții gastrice pe cale clasică. Această decizie de favorizare a rezecțiilor gastrice la pacienții prezentați în urgență este bazată mai mult pe experiența clinicii (de profil fiind chirurgia de urgență) cu rezultate bune la acești pacienți, iar date din literatura recentă par să susțină această abordare în cazuri selecționate [43].…”

Section: Discuțiiunclassified

Predictive factors of postoperative outcome for patients with gastric resections following emergency presentation for gastric cancer

Drăghici¹

2022

Surgery

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IntroducereCancerul gastric este una dintre cele mai frecvente patologii maligne și a patra cauză de deces în rândul pacienților oncologici la nivel mondial cu aproximativ 1.1 milioane de noi cazuri diagnosticate anual și aproximativ 800000 de decese anual [1]. Frecvența apariției acestuia crește cu vârsta, fiind rar întalnit la pacienți mai tineri de 45 de ani [2]. În pofida progresului în managementul oncologic și chirurgical al acestei patologii, rata mortalității rămâne ridicată, în special în populația vârstnică și conform unui studiu recent valorile cele mai crescute sunt

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Section: Discuțiiunclassified

Predictive factors of postoperative outcome for patients with gastric resections following emergency presentation for gastric cancer

Drăghici¹

2022

Surgery

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The language of palliative surgery: A scoping review

Kopecky,

Monton,

Arbaugh

et al. 2024

Surgical Oncology Insight

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Palliative Gastrectomy Versus Gastric Bypass for Symptomatic Clinical Stage Iv Gastric Cancer: A Propensity Score Matching Analysis

PINTO,

PEREIRA,

RIBEIRO JUNIOR

et al. 2023

ABCD, arq. bras. cir. dig.

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BACKGROUND: Patients with clinical stage IV gastric cancer may require palliative procedures to manage complications such as obstruction. However, there is no consensus on whether performing palliative gastrectomy compared to gastric bypass brings benefits in terms of survival. AIMS: To compare the overall survival of patients with distal obstructive gastric cancer undergoing palliative surgical treatment, using propensity score matching analysis. METHODS: Patients who underwent palliative bypass surgery (gastrojejunostomy or partitioning) and resection between the years 2009 and 2023 were retrospectively selected. Initial and postoperative clinicopathological variables were collected. RESULTS: 150 patients were initially included. The derived group (n=91) presented more locally invasive disease (p<0.01), greater degree of obstruction (p<0.01), and worse clinical status (p<0.01), while the resected ones (n= 59) presented more distant metastasis (p<0.01). After matching, 35 patients remained in each group. There was no difference in the incidence of postoperative complications, but the derived group had higher 90-day mortality (p<0.01). Overall survival was 16.9 and 4.5 months for the resected and derived groups, respectively (p<0.01). After multivariate analysis, hypoalbuminemia (hazard ratio — HR=2.02, 95% confidence interval — 95%CI 1.17–3.48; p=0.01), absence of adjuvant chemotherapy (HR=5.97; 95%CI 3.03–11.7; p<0.01), and gastric bypass (HR=3,28; 95%CI 1.8–5.95; p<0.01) were associated with worse survival. CONCLUSIONS: Palliative gastrectomy was associated with greater survival and lower postoperative morbidity compared to gastric bypass. This may be due to better local control of the disease, with lower risks of complications and better effectiveness of chemotherapy.

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Impact of gastrectomy for incurable advanced gastric cancer in urgent situations in the elderly

Cited by 3 publications

References 21 publications

Predictive factors of postoperative outcome for patients with gastric resections following emergency presentation for gastric cancer

Predictive factors of postoperative outcome for patients with gastric resections following emergency presentation for gastric cancer

The language of palliative surgery: A scoping review

Palliative Gastrectomy Versus Gastric Bypass for Symptomatic Clinical Stage Iv Gastric Cancer: A Propensity Score Matching Analysis

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