Impact of fresh-cycle variables on the implantation potential of cryopreserved-thawed human embryos

The effect of cycle regimen used for endometrium preparation on the outcome of day 3 frozen embryo transfer cycle

“…Different IVF centers are using different approaches with regard to endometrial preparation with gonadotrophins/GnRH agonists and exogenous estrogens for ''controlled'' FRET. Our data support the observations of others that the outcome of FRET is similar in natural and in artificial programmed/stimulated steroid supplemental cycles (3,5). Our result indicates that there is no benefit from using a natural or a hormone replacement scheme to increase the chance of pregnancy.…”

“…Nevertheless, FRET increases the (cumulative) pregnancy rate, reduces cost, is relatively simple to undertake, and can be accomplished in a shorter time period compared with repeated ''fresh'' cycles. Therefore, efforts to study the factors affecting success of FRET cycles have intensified (1)(2)(3)(4).…”

Factors associated with ovarian hyperstimulation syndrome (OHSS) and its effect on assisted reproductive technology (ART) treatment and outcome

“…Although the recent review by the Cochrane Collaboration did not find enough evidence to support routine cryopreservation (33), many IVF centers continue to utilize this method as a way of reducing the risk of OHSS (34). Increased use of embryo freezing in these high risk cases could have reduced the incidence of OHSS reported to the SART dataset.…”

Natural cycle is superior to hormone replacement therapy cycle for vitrificated-preserved frozen-thawed embryo transfer

“…Many factors influence the success rate of FET cycles [Urman et al 2007;Noyes et al 2009;Kovacs et al 2003;Yeung et al 2009;Salumets et al 2003], including number, grade, storage duration and developmental potential of the thawed embryo, cause of infertility, the endometrial thickness at the time of transfer, and the technique of the operator. Additionally, most of the retrospective trials have been small in scale with limited power.…”