Impact of First 10 Years of Post Menopause on Muscle Function, Muscle Mass and Bone Mineral Density in Adult Women

Kochi, Margarete Noriko; Marques, Nise Ribeiro; Costa, Gustavo de Carvalho da; Reis, João Batista Ribeiro da Silva; Paula, Francisco José Albuquerque de; Ferreira, Cristine Homsi Jorge; Abreu, Daniela Cristina Carvalho de

doi:10.4172/2329-9509.1000151

Cited by 1 publication

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“…Osteoporosis a silently progressing metabolic bone disease is widely prevalent in India leading to an increased fracture risk equally in both men and women [ 42 ]. The main cause of osteoporosis in women is due to the hormonal changes due to decrease in the estrogen levels in the blood [ 43 ]. Postmenopausal osteoporosis in women is often named as a silent disease which leads to decreased bone strength eventually leading to an increased fracture risk [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

A Comparative Study of Actinidia deliciosa and Garcinia mangostana in Ovariectomy-Induced Osteoporosis in Female Wistar Rats

Chitra

Sukumaran

Sivasubramanian

et al. 2017

BioMed Research International

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The present study was designed to evaluate antiosteoporotic activity of the fresh juice mixtures obtained from Actinidia deliciosa and Garcinia mangostana as well as the pericarp extract of Garcinia mangostana on postmenopausal osteoporosis. 3-month-old female Wistar rats were ovariectiomized and the treatment began 14 days after ovariectomy and continued for 40 days. Statistically significant changes were noticed in body weight, ash weight, bone mineral content, and femur length and weight followed by serum evaluation and histopathology of femur bone. Administration of the fresh juice mixtures of the fruits of Actinidia deliciosa and Garcinia mangostana prevented ovariectomy-induced bone loss. The administration of the fresh juice mixtures resulted in an increase in the femur length and weight, followed by an increase in the body weight as well as the calcium content obtained from the ash of the femur bone. It is evident that the fresh juice mixtures can be used as a remedy as well as a prophylactic for the prevention of postmenopausal osteoporosis. The present study showed that the combined effect of the fruit juice mixtures of Actinidia deliciosa and Garcinia mangostana was found to be a better treatment for postmenopausal osteoporosis when compared to the pericarp extract of Garcinia mangostana.

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Section: Discussionmentioning

confidence: 99%