Impact of fine-needle biopsy on management of patients with carcinoma of the pancreas

Ha, Mitty; Efremidis, SC; Hc, Yeh

doi:10.2214/ajr.137.6.1119

Cited by 48 publications

(9 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Higher accuracy rates for diagnosing pancreatic malignancy (85-100%) were reported for cytologic studies of preoperative fineneedle biopsies [20][21][22][23]. Accuracy rates of ultrasound-directed preoperative FNB with cytological proof of aspirated samples ranged between 64 and 89% [7,17,18,24]. In our series of pancreatic biopsies we were able to evaluate tissue fragments in 61% of cases and reached an overall accuracy of cytohistological studies of 92.9%.…”

Section: Discussionmentioning

confidence: 62%

Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms

Schwerk

Dürr

Schmitz-Moormann

1983

Gastrointest Radiol

View full text Add to dashboard Cite

Two hundred patients underwent ultrasound-guided percutaneous fine-needle aspiration biopsies of hepatic and pancreatic space-occupying lesions. In addition to the cytologic smear preparations (100%), tissue fragments and cores suitable for histological evaluation were obtained from aspirated samples in 84% of specimens from hepatic targets (n = 130) and in 61% of specimens from pancreatic lesions (n = 70). The prevalence of malignant disease was 78.5% in the liver study group and 74.3% in the patients undergoing pancreatic biopsies. The overall accuracy rate of cytohistologic readings for malignancy was 94.6% in liver biopsies and 92.9% in pancreatic biopsies with a high predictive value of positive results of 98% and 100%, respectively, and a less satisfying predictive value of negative results of 83.9% and 77.3%, respectively. Two false-positive diagnoses were encountered in the evaluation of cytologic smear preparations of hepatic aspirations. No serious complications occurred with the biopsy procedure. Ultrasound-guided fine-needle biopsy is recommended as a safe and reliable method for cytohistological confirmation of suspected hepatic and pancreatic malignancy.

show abstract

Section: Discussionmentioning

confidence: 62%

Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms

Schwerk

Dürr

Schmitz-Moormann

1983

Gastrointest Radiol

View full text Add to dashboard Cite

show abstract

“…The general indications for FNAB are: (1) to obtain pathological evidence of malignancy without exploratory laparotomy, (2) to obtain proof of metastasis as an aid to staging neoplasms, and (3) to differentiate between specific infections and malignancy. The technique as yet has limited application in the diagnosis of benign neoplastic conditions from osseous or abdominal sites and of primary bone sarcomas.…”

Section: Discussionmentioning

confidence: 99%

Radiologically‐guided Percutaneous Fine Needle Aspiration Biopsies of Abdominal and Osseous Lesions

Philips

Waugh

1984

Australian and New Zealand Journal of Medicine

View full text Add to dashboard Cite

The inductions, technique, complications and results of radiologically-guided percutaneous fine needle aspiration biopsy (FNAB) of abdominal and osseous sites performed over a four and a half year period at an Australian tertiary referral hospital are presented. FNAB provided a positive tissue diagnosis for malignancy in 79% of osseous and 78% of abdominal lesions with no false positive diagnoses in either series. Particular problems encountered and the methods employed to overcome them are discussed.

show abstract

“…The extent of tumor growth can reliably be shown by these noninvasive methods. Percutaneous fine needle biopsy to obtain histologic or cytologic confirmation [11,12] also obviates surgical exploration. Biliary drainage by transhepatic [13][14][15] or endoscopic [16] techniques has become an important palliative measure.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous transhepatic portography in pancreatobiliary carcinoma: Evaluation of resectability

Boetes

et al. 1982

Gastrointest Radiol

View full text Add to dashboard Cite

Direct portography using the percutaneous, transhepatic approach provides a rapid and accurate visualization of the portal, splenic, and superior mesenteric veins. In 7 patients with a malignant tumor of the pancreatobiliary region and in 1 patient with pancreatitis, the method was reliable in predicting resectability of the lesion.Pancreatic carcinoma is responsible for an increasing number of deaths. With the more widespread use of pancreatic imaging techniques such as computed tomography, ultrasound, endoscopic retrograde cholangiopancreatography (ERCP), and superselective angiography, and the use of fine needle biopsy for cytologic diagnosis, it can be expected that pancreatic tumors will be diagnosed in earlier stages of growth.Although a radical operation for a large tumor was barely possible in the past, the diagnosis of smaller tumors at present poses the problem of patient selection for surgery. A reliable determination of operability could save the patient from unnecessary surgery, and decrease the time and costs of hospitalization. Alternative palliative and therapeutic measures such as endoscopic or transhepatic biliary drainage, radiation and/or chemotherapy, could be instituted earlier. As the venous structures in the pancreatobiliary region (portal, splenic, and superior mesenteric veins) are critical in surgery, and veins in general show infiltration by tumor earlier and more frequently than arteries, we performed percutaneous transhepatic portography to evaluate operability in 8 patients suspected of having a pancreatobiliary tumor. Material and MethodsDuring 1980 and 1981, 8 patients with histologically confirmed or clinically suspected malignant tumors of the pancreatobiliary region were examined with percutaneous transhepatic portography (PTP). The technique of PTP was in accordance with that described in the literature [1, 2], i.e., a right-sided puncture through the liver under local anesthesia and placement of a catheter in the portal vein and its extrahepatic tributaries (splenic vein and superior mesenteric vein).Contrast medium (40 ml Angiografine 65%) was injected in the splenic and superior mesenteric veins at a rate of 8 ml/sec; 12 films were exposed in both frontal and lateral views at a rate of 1 film/sec. In 1 patient, the puncture was not readily successful. Selective angiography of the superior mesenteric artery was performed to localize the portal vein and to exclude portal vein thrombosis. Subsequent portal vein puncture then was successful. Obstructive jaundice was present in 5 patients. Percutaneous transhepatic biliary drainage was performed in 2 patients several days before PTP, and in 1 patient immediately before PTP.Two patients had surgical internal biliary drainage established at another hospital before referral for further treatment. One of these patients still had dilated intra-and extrahepatic bile ducts that were entered accidentally during the puncture attempts for portography. After the investigation, this patient complained of abdominal pain, and a short-lasting ...

show abstract

Impact of fine-needle biopsy on management of patients with carcinoma of the pancreas

Cited by 48 publications

References 16 publications

Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms

Ultrasound guided fine-needle biopsies in pancreatic and hepatic neoplasms

Radiologically‐guided Percutaneous Fine Needle Aspiration Biopsies of Abdominal and Osseous Lesions

Percutaneous transhepatic portography in pancreatobiliary carcinoma: Evaluation of resectability

Contact Info

Product

Resources

About