Impact of Family History and Germline Genetic Risk Single Nucleotide Polymorphisms on Long-Term Outcomes of Favorable-Risk Prostate Cancer
Florian Rumpf,
Anna Plym,
Jane B. Vaselkiv
et al.
Abstract:Purpose: Family history and germline genetic risk single nucleotide polymorphisms (SNPs) have been separately shown to stratify lifetime risk of prostate cancer. Here, we evaluate the combined prognostic value of family history of prostate and other related cancers and germline risk SNPs among patients with favorable-risk prostate cancer. Materials and Methods: A total of 1367 participants from the prospective Health Professionals Follow-up Study diagnosed with low-or favorable intermediaterisk prostate cancer… Show more
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