Impact of Endoscopy on Management of Chronic Abdominal Pain in Children

Thakkar, Kalpesh; Dorsey, Faith; Gilger, Mark A.

doi:10.1007/s10620-010-1315-1

Cited by 14 publications

(11 citation statements)

References 16 publications

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“…Among children who underwent EGD for abdominal pain, the prevalence of EoE ranged from 2.1% to 4.9% (29)(30)(31), whereas the prevalence of EoE among children with celiac disease ranged from 1.1% to 5.1% (21)(22)(23)(24)(25). The prevalence of EoE among children post-liver transplantation were 2.4% and 3.0% (26,27).…”

Section: Resultsmentioning

confidence: 99%

Incidence and Prevalence of Eosinophilic Esophagitis in Children

Soon

Butzner²,

Kaplan³

et al. 2013

J. pediatr. gastroenterol. nutr.

132

106

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During the last 2 decades, the incidence and prevalence of EoE in children have increased significantly; however, the population-based incidence and prevalence of EoE vary widely across geographic variations, potentially because of variations in case of ascertainment between centers. Because EoE is common among children with food impaction and dysphagia, children with this presenting complaint should be rapidly identified at triage for timely endoscopic assessment.

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Section: Resultsmentioning

confidence: 99%

Incidence and Prevalence of Eosinophilic Esophagitis in Children

Soon

Butzner²,

Kaplan³

et al. 2013

J. pediatr. gastroenterol. nutr.

132

106

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show abstract

“…Overall, the most frequent indication for EGD in childhood is CAP [27]. In light of the fact, that most of these performed EGDs do not yield therapeutically relevant pathological findings, making the indication to perform EGD in these patients should be preceded by a much more rigorous diagnostic filter.…”

Section: Discussionmentioning

confidence: 99%

Common Indications and The Diagnostic Yield of Esophagogastroduodenoscopy in Children with Gastrointestinal Distress

et al. 2018

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“…Published data indicate that at least one-third of children with histologic esophagitis experience medical management changes. 12 Thus, reflux esophagitis may be an important finding in children with CAP, because it often leads to a trial of PPI therapy or an adjustment of prior PPI treatment.…”

Section: Discussionmentioning

confidence: 99%

Outcomes of Children After Esophagogastroduodenoscopy for Chronic Abdominal Pain

Thakkar

Chen

Tessier

et al. 2014

Clinical Gastroenterology and Hepatology

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BACKGROUND & AIMS Chronic abdominal pain is the most common indication for esophagogastroduodenoscopy (EGD) in children. However, little is known about the accuracy of EGD-based diagnosis or the outcomes of the patients who undergo this procedure. We examined the diagnostic yield of EGD and short-term outcomes of children who underwent this procedure for chronic abdominal pain. METHODS We conducted a prospective study of 290 children (4–18 years old; mean age, 11.9 – 3.5 years; 93 girls) who underwent EGD for the primary indication of chronic abdominal pain (216 with at least 1 alarm feature) at a US pediatric gastroenterology referral center. We collected data on demographic features (age, sex), clinical characteristics (alarm features, Rome III criteria), and EGD results for each patient. All subjects with diagnostic lesions were followed for at least 1 year after EGD to determine short-term outcomes. RESULTS Overall, EGD provided an accurate diagnosis for 109 children (38%). Diagnoses included esophagitis (21.0%), eosinophilic gastroenteritis (4.1%), eosinophilic esophagitis (3.8%), Helicobacter pylori infection (2.0%), celiac disease (0.6%), and Crohn’s disease (0.4%). Short-term outcomes were available for 81% of patients with diagnostic findings, and medical therapy was effective in approximately 67% of these children. CONCLUSIONS EGD is valuable for the diagnosis of children with abdominal pain, with a 38% diagnostic yield. EGD identified disorders for which medical therapy was effective in 67% of children during the year after diagnosis.

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Impact of Endoscopy on Management of Chronic Abdominal Pain in Children

Abstract: The overall rate of management change after endoscopic evaluation in children with CAP was approximately 66% (61/92). Management outcome was not associated with type of histologic findings.

Cited by 14 publications

References 16 publications

Incidence and Prevalence of Eosinophilic Esophagitis in Children

Incidence and Prevalence of Eosinophilic Esophagitis in Children

Common Indications and The Diagnostic Yield of Esophagogastroduodenoscopy in Children with Gastrointestinal Distress

Outcomes of Children After Esophagogastroduodenoscopy for Chronic Abdominal Pain

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