Impact of Different Dietary Components on Gene Expression of Leptin and Adiponectin in Adipose Tissue of Obese Rats

Sadek, M. A.; Darwish, Samah F.; El-Rhman, Amira; El-Fadl, Huda M Ismail Abo

doi:10.9734/ijbcrr/2016/30489

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“…Diet-induced obesity is associated with up-regulation of leptin and down-regulation of adiponectin mRNA along with high expression of mRNA encoding proinflammatory cytokines in adipose tissues. 45 The FTA up-regulated adiponectin mRNA and decreased leptin mRNA expression, although NKS-3 failed to significantly decrease the latter in adipose tissues of HFD-fed mice. Leptin is also a proinflammatory adipokine.…”

Section: Discussionmentioning

confidence: 92%