Impact of Different Criteria on Type 2 Diabetes Remission Rate After Bariatric Surgery

Más-Lorenzo, Antonio; Benaiges, David; Flores-Le-Roux, Juana A.; Pedro‐Botet, Juan; Ramón, José́; Parri, A.; Villatoro, Montserrat; Chillarón, Josep; Pera, Manuel; Grande, Luís; Goday, Alberto

doi:10.1007/s11695-014-1282-2

Cited by 41 publications

(21 citation statements)

References 35 publications

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“…The BMI was calculated as the weight in kilograms divided by the height in square meters. The percentage of EWL (%EWL) was based on the weight in excess of that corresponding to a BMI of 25 kg/m 2 for each patient 14 …”

Section: Methodsmentioning

confidence: 99%

Preoperative Predictors of Weight Loss at 4 Years Following Bariatric Surgery

et al. 2015

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Section: Methodsmentioning

confidence: 99%

Preoperative Predictors of Weight Loss at 4 Years Following Bariatric Surgery

et al. 2015

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“…To date, the most effective treatment for both weight reduction and glycaemic control is bariatric (metabolic) surgery, with a 58% to 95% reported rate of T2D remission, particularly following either a biliopancreatic diversion (BPD) or a Roux‐en‐Y gastric bypass (RYGB). The percentage of patients achieving T2D remission varies, depending on how diabetes remission is defined . Despite high remission rates in non‐insulin treated T2D patients, lower remission rates occur in patients receiving IT, both in the short‐ and mid‐term, with figures ranging from 19.3% to 75.2% .…”

Section: Therapeutic Interventionsmentioning

confidence: 99%

Insulin‐associated weight gain in obese type 2 diabetes mellitus patients: What can be done?

Brown

Guess

Dornhorst

et al. 2017

Diabetes Obesity Metabolism

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Insulin therapy (IT) is initiated for patients with type 2 diabetes mellitus when glycaemic targets are not met with diet and other hypoglycaemic agents. The initiation of IT improves glycaemic control and reduces the risk of microvascular complications. There is, however, an associated weight gain following IT, which may adversely affect diabetic and cardiovascular morbidity and mortality. A 3 to 9 kg insulin-associated weight gain (IAWG) is reported to occur in the first year of initiating IT, predominantly caused by adipose tissue. The potential causes for this weight gain include an increase in energy intake linked to a fear of hypoglycaemia, a reduction in glycosuria, catch-up weight, and central effects on weight and appetite regulation. Patients with type 2 diabetes who are receiving IT often have multiple co-morbidities, including obesity, that are exacerbated by weight gain, making the management of their diabetes and obesity challenging. There are several treatment strategies for patients with type 2 diabetes, who require IT, that attenuate weight gain, help improve glycaemic control, and help promote body weight homeostasis. This review addresses the effects of insulin initiation and intensification on IAWG, and explores its potential underlying mechanisms, the predictors for this weight gain, and the available treatment options for managing and limiting weight gain.

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“…Remission rates of diabetes vary greatly and even more so depending on which criteria is used to consider remission. Some studies have quoted a remission rate of 43-92% [14].…”

Section: Discussionmentioning

confidence: 99%

Course of Diabetic retinopathy following bariatric surgery in patients with Type 2 diabetes: the immediate and late impact of glycaemic control

Varadhan¹,

Kalidindi²,

Gill³

et al. 2017

Integr Obesity Diabetes

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Background: Diabetic Retinopathy (DR) is a significant complication of diabetes mellitus, which can worsen during rapid fluctuations in glycaemic control. Bariatric surgery can cause sudden improvement in diabetes control which can affect DR in the short term.Objectives: To assess the immediate and late impact of bariatric surgery on DR status in patients with type 2 diabetes mellitus and to evaluate the need for continuing retinal screening despite improvement or remission of diabetes. Methods:A retrospective clinical observational analysis was conducted on patients who underwent bariatric surgery for type 2 diabetes. One-year pre-operative and all post-operative retinal screen images were obtained and graded using the national diabetic eye screen programme grading. Conclusion:Our study demonstrates the variable nature of progression of DR after bariatric surgery in patients with type 2 diabetes mellitus. Long term trials are needed to identify the pattern of progression and to identify risk factors.

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Impact of Different Criteria on Type 2 Diabetes Remission Rate After Bariatric Surgery

Abstract: T2DM remission rate varies widely depending on the criteria used for its definition. Remission occurred sooner after LRYGB when the strictest criteria to define remission were used.

Cited by 41 publications

References 35 publications

Preoperative Predictors of Weight Loss at 4 Years Following Bariatric Surgery

Preoperative Predictors of Weight Loss at 4 Years Following Bariatric Surgery

Insulin‐associated weight gain in obese type 2 diabetes mellitus patients: What can be done?

Course of Diabetic retinopathy following bariatric surgery in patients with Type 2 diabetes: the immediate and late impact of glycaemic control

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