Impact of Diet Composition on Insulin Resistance

Martins, Fátima O.; Conde, Sílvia V.

doi:10.3390/nu14183716

Cited by 9 publications

(4 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4,9,10 Studies have showed the distinct impacts of intrinsic versus added sugars on metabolic health, with a particular focus on fruit juices versus sugary solutions. 35,36 Mediterranean diet's potential for improving insulin sensitivity and metabolic health, contrasted with high-protein diets' effectiveness in specific populations of central India. 37 Chronic energy oversupply from food, coupled with insufficient physical activity, leads to overweight, abdominal adiposity, insulin resistance, and eventually Type 2 Diabetes Mellitus (T2DM).…”

Section: Discussionmentioning

confidence: 99%

Role of Triglyceride to High Density Lipoprotein (TG/HDL) Ratio as A Marker of Insulin Resistance in Adults of Central India: A Narrative Review

Khan,

Quazi,

Wanjari

2024

Natl J Community Med

View full text Add to dashboard Cite

One of the main risk factors for the onset of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) is insulin resistance (IR). But because there aren't many easy-to-use and trustworthy biomarkers or tests, the entity is frequently under diagnosed. The present review was performed with an aim to provide the available data regarding the role or efficacy of TG/HDL ratio as an indicator of IR in adults of central India, a region popular for high prevalence of T2DM and CVD. An extensive search of all materials related to the topic was carried out in the PubMed search engine. Relevant research articles focusing on use of TG/HDL as a marker of insulin resistance published in the period 2002 to 2023 were included in the review. A total of 33 articles were selected based upon their suitability with the current review objectives and analyzed. The review concludes that TG/HDL ratio is a simple, affordable, and feasible marker of IR that can be used in economically poor regions of the India or world for screening IR and risk stratification of T2DM and CVD in adults. However, more studies are needed in India and all over the world to validate this marker and its cut-off values.

show abstract

Section: Discussionmentioning

confidence: 99%

Role of Triglyceride to High Density Lipoprotein (TG/HDL) Ratio as A Marker of Insulin Resistance in Adults of Central India: A Narrative Review

Khan,

Quazi,

Wanjari

2024

Natl J Community Med

View full text Add to dashboard Cite

show abstract

“…Dietary fiber consumption is also essential for regulating insulin metabolism. Whole grains, fruits, vegetables, and legumes are examples of high-fiber diets that slow down the digestion and absorption of carbs, reducing blood sugar rises and promoting improved insulin regulation [44,45].…”

Section: Effect Of Dietary Gi and Gl Indexes On Glucose And Insulin H...mentioning

confidence: 99%

Glycemic Index and Glycemic Load Estimates in the Dietary Approach of Polycystic Ovary Syndrome

Manta,

Paschou,

Isari

et al. 2023

Nutrients

View full text Add to dashboard Cite

Polycystic ovary syndrome is a common endocrine disorder characterized by hormonal imbalances and various metabolic abnormalities linked to insulin resistance via a vicious cycle. Genetic and environmental factors underlie its pathogenesis and evolution. Nutrition, in terms of nutrient composition, dietary patterns, endocrine-disrupting chemicals, and food processing and preparation, has gained significant attention in the pathogenesis and the therapeutic approach of polycystic ovary syndrome. Carbohydrate intake seems to be a critical point in the diet assignment. Glycemic index and glycemic load constitute indexes of the impacts of dietary carbohydrates on postprandial glucose levels. Numerous studies have indicated that a high glycemic index and glycemic load diet may exacerbate insulin resistance, a key feature of the syndrome, and offer a risk for its development and its complications. Conversely, low-glycemic index and low-glycemic load diets seem to improve insulin sensitivity, regulate menstrual cycles, and mitigate the risk of comorbidities associated with polycystic ovary syndrome, such as obesity, alterations in body composition, type 2 diabetes, cardiovascular disease, and quality of life. This comprehensive review aims to explore the relevance of nutrition and more specifically, the association of glycemic index and glycemic load with the various aspects of polycystic ovary syndrome, as well as to assess the potential benefits of manipulating those indexes in the dietary approach for the syndrome.

show abstract

“…Sucrose, fructose, glucose, starch hydrolysates, and other isolated sugar preparations added during food preparation and manufacturing are included in the added sugars category [53]. It seems consensual that added sugars have a noxious role in the development of metabolic diseases and that sugars that are intrinsically present in food seem to have more harmless impacts on dysmetabolic conditions [54,55]. For example, in a study performed by Monteiro-Alfredo [55], it was shown, in Goto-Kakizaki rats, that the ad libitum ingestion of sugary solutions for 4 weeks impaired energy balance regulation, leading to higher caloric intake, weight gain, fasting hyperglycaemia, insulin intolerance, and impaired oxidative stress/glycation markers than the ad libitum intake of fruit juices, demonstrating the different impacts of added vs. intrinsically present sugars in the metabolism.…”

Section: Impact Of Sugar Consumption On Food Behaviourmentioning

confidence: 99%

Impact of Sugars on Hypothalamic Satiety Pathways and Its Contribution to Dysmetabolic States

Capucho

Conde

2022

Diabetology

Self Cite

View full text Add to dashboard Cite

Food behaviour is a complex and multifaceted cooperation between physiologic, psychological, social, and genetic factors, influencing meal timing, amount of food intake, food preferences, and food selections. Deregulation of the neurobiological mechanisms controlling food behaviour underlies the development of obesity and type 2 diabetes, two epidemics of the present century. Several brain nuclei are involved in the regulation of the different components of food behaviours; the hypothalamus is the key in controlling appetite and energy homeostasis. In this review, we will explain the role of the hypothalamus in the control of food intake and its interplay with other brain nuclei important in food behaviour. We will also highlight the deregulation of satiety pathways in type 2 diabetes and obesity and the mechanisms behind this deregulation. Finally, knowing that there are different categories of sugars and that they differently impact food behaviours, we will review in a concise manner the studies referring to the effects of sugars in satiety and reward pathways and their impacts on metabolic diseases.

show abstract

Impact of Diet Composition on Insulin Resistance

Abstract: Insulin resistance is a complex condition in which the body does not respond adequately to insulin, a hormone secreted by the pancreas with an essential role in the regulation of blood sugar levels [...]

Cited by 9 publications

References 40 publications

Role of Triglyceride to High Density Lipoprotein (TG/HDL) Ratio as A Marker of Insulin Resistance in Adults of Central India: A Narrative Review

Role of Triglyceride to High Density Lipoprotein (TG/HDL) Ratio as A Marker of Insulin Resistance in Adults of Central India: A Narrative Review

Glycemic Index and Glycemic Load Estimates in the Dietary Approach of Polycystic Ovary Syndrome

Impact of Sugars on Hypothalamic Satiety Pathways and Its Contribution to Dysmetabolic States

Contact Info

Product

Resources

About