Impact of Diastolic and Systolic Blood Pressure on Mortality: Implications for the Definition of “Normal”

Taylor, Brent C.; Wilt, Timothy J; Welch, H. Gilbert

doi:10.1007/s11606-011-1660-6

Cited by 79 publications

(52 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Adjusting for confounders and residential selection bias using CEM, we found that those who consistently lived in poor neighborhoods had roughly 46% higher odds of being obese and 52% greater odds of being hypertensive in young adulthood than did those with no exposure to neighborhood poverty. Further, those who exited versus never lived in neighborhood poverty had significantly higher diastolic blood pressure, which is a stronger predictor of early mortality for young adults than is systolic blood pressure (67). Minimally adjusted models revealed more significant patterns, but these were not robust to adjustment for residential selection bias.…”

Section: Resultsmentioning

confidence: 88%

Associations of Continuity and Change in Early Neighborhood Poverty With Adult Cardiometabolic Biomarkers in the United States: Results From the National Longitudinal Study of Adolescent to Adult Health, 1995–2008

Lippert¹,

Evans²,

Razak³

et al. 2017

American Journal of Epidemiology

View full text Add to dashboard Cite

Limitations of extant research on neighborhood disadvantage and health include general reliance on point-intime neighborhood measures and sensitivity to residential self-selection. Using data from the US Census and the 1995-2008 National Longitudinal Study of Adolescent to Adult Health, we applied conventional methods and coarsened exact matching to assess how cardiometabolic health varies among those entering, exiting, or remaining in poor and nonpoor neighborhoods. Within the full sample (n = 11,767), we found significantly higher systolic and diastolic blood pressures among those who entered or consistently lived in poor neighborhoods relative to those who never lived in poor neighborhoods. Obesity was similarly more common among those who originated from poor neighborhoods than among those who originated from nonpoor neighborhoods. Having exited poor neighborhoods was associated with lower systolic blood pressure than was consistent residence in low-income communities. Among the matched sample (n = 9,727), results adjusted for confounders and residential selfselection revealed fewer significant contrasts. Compared with peers who had no neighborhood poverty exposure, those who consistently lived in poor neighborhoods had 46% and 52% higher odds of being obese or hypertensive, respectively. Those who exited neighborhood poverty had significantly higher diastolic blood pressures than those who had never lived in poor neighborhoods. These findings underscore the importance of past as well as current residential circumstances for cardiometabolic health.

show abstract

Section: Resultsmentioning

confidence: 88%

Associations of Continuity and Change in Early Neighborhood Poverty With Adult Cardiometabolic Biomarkers in the United States: Results From the National Longitudinal Study of Adolescent to Adult Health, 1995–2008

Lippert¹,

Evans²,

Razak³

et al. 2017

American Journal of Epidemiology

View full text Add to dashboard Cite

show abstract

“…Low ADATMS13 levels were positively correlation with low diastolic and mean arterial blood pressure (MAP) and it has been observed [27,28] that low MAP is a significant predictor of organ dysfunction. The significance of isolated low diastolic blood pressure with mortality has been studied, but these studies were done in normal and cardiogenic shock patients [29,30]. Further studies are needed to determine its significance in patients with severe sepsis and septic shock.…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of ADAMTS13 in patients with severe sepsis and septic shock

Azfar

Khan

Habib

et al. 2017

CIM

View full text Add to dashboard Cite

Prognostic value of ADAMTS13 in patients with severe sepsis and septic shock Abstract Purpose: ADAMTS13 level was evaluated as a predictor of mortality in patients with severe sepsis and septic shock, and compared with Acute Physiology and Chronic Health Evaluation II (APACHE II) scores.Methods: This prospective observational study was conducted in the Medical and Surgical Intensive Care Units of King Khalid University Hospital. Detailed clinical evaluations were performed on 84 patients (56.08±18.18 years of age) with severe sepsis and septic shock. ADAMTS13 levels were determined (three blood samples at 24 hours intervals) and APACHE II scores, hematological profiles, indices of organ hypo-perfusion, renal functions and coagulation profiles were recorded. Primary outcome was 30 days ICU mortality and secondary outcomes were its comparison with APACHE II score, length of ICU stay and use of vasopressor agents.Results: Hypertension (53.6%) and diabetic mellitus (45.2%) were the commonest comorbidities. The median ADAMTS13 levels were 336.65, 339.35 and 313.9, respectively. ROC analysis showed maximum area under the curve for second ADAMTS13 (AUC=0.760) compared with first (AUC=0.660) and third samples (AUC=0.707) and APACHE II scores (AUC=0.662). Patients were divided into low and high ADAMTS13 groups according to the best cut-off point. Mortality was high in the low ADAMTS13 level group [OR=4.5]and was significantly associated with age, DBP, ADAMTS13, APACHE II score, DIC score and platelet count. ADAMTS13 (OR=5.3), APACHE II (OR=4.13) and DIC scores (OR=7.32) were significant risk factors for mortality.Conclusions: Low ADAMTS13 was associated with increased mortality in patients with severe sepsis and septic shock and was comparable to APACHE II scores for predicting mortality.

show abstract

“…Como se evidenció, un IMC mayor 25 kg/m 2 y presentar un PC elevado, son factores independientes para el desarrollo de HTA. Datos similares se han identificado en la literatura, tanto en población occidental 21,22 como oriental 1,11,23 . En relación a los estilos de vida, las personas hipertensas reportaron menores niveles de AF y de transporte que aquellas personas con presiones normales (p < 0,0001).…”

Section: Discussionunclassified