Impact of Diabetic Retinopathy on Cardiac Outcome After Coronary Artery Bypass Graft Surgery: Prospective Observational Study

Retinal Arteriolar Narrowing and Left Ventricular Remodeling

“…This is consistent with findings from the ARIC study (19) and other studies showing association of retinopathy signs with the development of heart failure after coronary artery bypass surgery in persons with diabetes (20,21). Thus, our data provide further support to the theory that in diabetic patients, myocardial ischemia induced by coronary microvascular disease is an important risk factor for LV dysfunction, even in the absence of epicardial coronary atherosclerosis (41).…”

“…Changes in the retinal vasculature, reflected as retinopathy signs, also have been shown to predict heart failure risk in the general population (19) and in patients after coronary artery bypass surgery (20,21), further supporting a link between the microvascular process and the development of clinical heart failure. Whether retinal microvascular signs are related to early subclinical morphologic alterations and remodeling in the heart in people without symptomatic heart failure is unclear.…”

Diabetic Retinopathy and Coronary Implantation of Sirolimus‐Eluting Stents

“…So far, however, few studies have reported the association between diabetic retinopathy and the outcomes following coronary revascularization. Previously, we demonstrated that status of retinopathy is closely related to the outcomes after coronary bypass surgery in diabetic patients 12,13 . Briguori et al reported the association between diabetic retinopathy and adverse cardiac events after percutaneous coronary intervention with bare metal stents 14 .…”

In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery

“…Therefore, CABG could offer the most benefit to NPDR patients. Although congestive heart failure was not included in the adverse cardiac events because of the retrospective nature of this study, we showed previously that PDR patients are at high risk for congestive heart failure after CABG, suggesting that PDR patients have irreversible diabetic cardiomyopathy [13]. NPDR patients usually have less severe renal and cardiac functional impairment compared with PDR patients.…”