Impact of Diabetes on the Severity of Liver Disease

Systemic abnormalities in liver disease

“…Insulin resistance is also reported to be closely associated with the progression of fibrosis [52] . Diabetes mellitus is considered to increase the risk of the development of hepatocellular carcinoma and to increase mortality [53,54] . T h e m o n i t o r i n g o f b l o o d g l u c o s e s h o u l d b e performed on patients with chronic HCV infection, and in particular on those with advanced fibrosis, and appropriate treatment may be required when diabetes mellitus is diagnosed.…”

Protective effect of aqueous extract of Feronia elephantum correa leaves on thioacetamide induced liver necrosis in diabetic rats

“…Such diabetes is known as hepatogenous diabetes (HD) [2] and said to be associated with diabetic hepatopathy. Nonalcoholic fatty liver disease (NAFLD), alcohol, hepatitis C virus (HCV) and haemochromatosis are often associated with DM [3] . On the other hand, about 96% of patients with cirrhosis may be glucose intolerant and 30% may be clinically diabetic [3] .…”

“…Nonalcoholic fatty liver disease (NAFLD), alcohol, hepatitis C virus (HCV) and haemochromatosis are often associated with DM [3] . On the other hand, about 96% of patients with cirrhosis may be glucose intolerant and 30% may be clinically diabetic [3] . Therefore, the aetiology of liver disease is becoming more important in the incidence and management of DM.…”

Cardiovascular Disease, Cancer, and Mortality Among People With Type 2 Diabetes and Alcoholic or Nonalcoholic Fatty Liver Disease Hospital Admission

“…There is evidence of a bi-directional relationship between liver disease and T2DM. Both ALD and NAFLD appear to be risk factors for T2DM, and T2DM is a risk factor for more severe liver disease in people with ALD or NAFLD (1)(2)(3)(4)(5)(6). The increased risk of CVD, cancer and mortality among people with type 2 diabetes, compared to people without diabetes, is well known (7)(8)(9).…”