Impact of diabetes on cognitive function among older Latinos

Wu, Jun; Haan, Mary N.; Liang, Jersey; Ghosh, Debashis; González, Hector M.; Herman, William H.

doi:10.1016/s0895-4356(03)00077-5

Cited by 95 publications

(81 citation statements)

References 30 publications

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“…Finally, prospective epidemiological studies also show a relationship between cognitive decline and clinical markers associated with hyperglycaemia, e.g. use of glucose-lowering medication, diabetes duration and diabetes complications [46,48,49,54,56,64]. The overview presented in this study is limited by several factors.…”

Section: Discussionmentioning

confidence: 91%

Cognitive decline and dementia in diabetes—systematic overview of prospective observational studies

2005

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Aims/hypothesis: We systematically reviewed and summarised prospective data relating diabetes status to changes in cognitive function over time. Methods: Published reports of longitudinal studies that described assessment of cognitive function in people with diabetes were sought. Studies were included if they assessed cognitive function in participants with diabetes at the beginning and at follow-up. Studies were excluded if they had (1) a follow-up period of less than 1 year, (2) a rate of loss to followup in excess of 30%, or (3) described selected subgroups. Change in cognitive function was recorded as either the mean change in score and/or the proportion of individuals developing various degrees of change in cognitive function. A pooled estimate was calculated for the latter. Results: Of 1,165 abstracts and titles initially identified, 25 articles met the inclusion and exclusion criteria. Individuals with diabetes had a 1.2-to 1.5-fold greater change over time in measures of cognitive function than those without diabetes. When assessed by the Mini-Mental State Exam and the Digit Symbol Span tests, a diagnosis of diabetes increased the odds of cognitive decline 1.2-fold (95% CI 1.05-1.4) and 1.7-fold (95% CI 1.3-2.3), respectively. The odds of future dementia increased 1.6-fold (95% CI 1.4-1.8). Conclusions/ interpretation: Compared to people without diabetes, people with diabetes have a greater rate of decline in cognitive function and a greater risk of cognitive decline. Cognitive dysfunction should therefore be added to the list of chronic complications of diabetes.

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Section: Discussionmentioning

confidence: 91%

Cognitive decline and dementia in diabetes—systematic overview of prospective observational studies

2005

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“…We ascertained prevalence of diabetes and stroke as described (27 ). Briefly, participants who met one or more of the following criteria were characterized as having diabetes: (a) fasting plasma glucose Ն126 mg/dL (Ն7.0 mmol/L); (b) antidiabetic medication use; (c) self-report or physician's diagnosis of diabetes.…”

Section: Ascertainment Of Diabetes and Strokementioning

confidence: 99%

Fraction of Total Plasma Vitamin B12 Bound to Transcobalamin Correlates with Cognitive Function in Elderly Latinos with Depressive Symptoms

et al. 2008

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“…Similarly although some longitudinal studies report null findings [9,10], most have found that diabetes is related to either cognitive decline or incident dementia [11][12][13][14][15][16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Glucoregulation has Greater Impact on Cognitive Performance than Macro-vascular Disease in Men with type 2 Diabetes: Data from the Caerphilly Study

et al. 2005

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Impact of diabetes on cognitive function among older Latinos

Cited by 95 publications

References 30 publications

Cognitive decline and dementia in diabetes—systematic overview of prospective observational studies

Cognitive decline and dementia in diabetes—systematic overview of prospective observational studies

Fraction of Total Plasma Vitamin B12 Bound to Transcobalamin Correlates with Cognitive Function in Elderly Latinos with Depressive Symptoms

Glucoregulation has Greater Impact on Cognitive Performance than Macro-vascular Disease in Men with type 2 Diabetes: Data from the Caerphilly Study

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