Impact of daily consumption of Moringa (<i>Moringa oleifera</i>) dry leaf powder on iron status of Senegalese lactating women

Abstract

A randomized study was conducted to test the efficacy of Moringa powder on iron status and weight gain in women. In an open-labelled randomized trial, 82 moderately anaemic, lactating women, aged 26.7± 6.5 years, received a weekly dose of either 100g of Moringa powder(Moringa group) or 120 mg iron sulphate with 0.5 mg folic acid (Control group). Data from 64 women (33 from Moringa group and 31 from Control group) were analyzed. Baseline parameters, socioeconomic , anthropometry, haematology, plasma ferritin, and acute phase proteins were comparable in both groups. Low plasma ferritin (< 12 μg/l) indicating iron deficiency was found in 13 and 14 women from the Moringa and Control groups, respectively. After 3 months of treatment, mean haemoglobin concentrations significantly increased in both groups (p<0.001) but iron stores were unchanged in the Moringa group while they significantly increased in the Control group indicating that consumption of Moringa leaves failed to restore iron stores in anaemic subjects. A slight improvement was observed in the prevalence of anaemia in both groups but anaemia still persisted due to other reasons than iron deficiency anaemia. None of the groups gained weight during the 3 months. However, the average weight lost was less important in the Moringa group (-0.8 ± 2.1 kg) compared to the control group (-1.2± 2.3 kg) but the difference was not significant (p=0.45).The amount of digestible protein in the powder could suggest that the consumption of Moringa was beneficial to the rural women by preventing weight loss during the rainy season. Micronutrient status improvement of vulnerable people in developing countries like Senegal should combine diet-based strategies through production and consumption of animal derived food, vegetable, fruits and food fortification program. However, Moringa Oleifera is one example of local food that can be used in nutritional intervention program, but its use needs additional rigorous clinical trials to confirm its nutritional benefits.

Contribution of Amaranthus cruentus and Solanum macrocarpon Leaves Flour to Nutrient Intake and Effect on Nutritional Status of Rural School Children in Volta Region, Ghana

“…e causes of anaemia are multifactorial. We suggest, similarly to Idohou-Dossou et al [25], that the residual anaemia in the intervention group could be due to deficiencies of other nutrients (such as folic acid and ascorbic acid) in addition to iron and vitamin A, antinutritional factors (polyphenols and phytic acid), and infection (malaria in the case of the present study). As ACSMLVF is a good source of micronutrients (iron, zinc, and beta-carotene), it may have the potential to control nutritional anaemia in relation to deficiencies of iron, zinc, and vitamin A. Malaria infection is known to promote anaemia.…”

“…As ACSMLVF is a good source of micronutrients (iron, zinc, and beta-carotene), it may have the potential to control nutritional anaemia in relation to deficiencies of iron, zinc, and vitamin A. Malaria infection is known to promote anaemia. It is possible, as suggested by previous studies [25], that malaria and other infections could partially explain the prevailing anaemia condition of the intervention group at the end of the study. e prevalence of malaria infection increased (but nonsignificantly) in the participants at the end of the study.…”

Effect of Moringa oleifera Leaves Extract Against Hematology and Blood Biochemical Value of Patients with Iron Deficiency Anemia

“…When compared with research of Idohou-Dossou, et al 2011, a significant increase seen in the moringa group and control group with consecutive values (1.3 ± 2.4) pg, p = 0.001 and ((1.7 ± 2.05) pg, p = 0.001. 14 Mean erythrocyte hemoglobin levels or MCHC for Moringa group increased significantly with a mean difference of 2.459 ± 2.86 g / dl, p = 0.003, while in the control group were not significantly decrease (0806 ± 2.81 g / dl) and p = 0.241. It happened due to the influence of MCV and MCH values were also decreased.…”

“…In the Moringa group 0.4 ± 6.9fL and p = 0.443 and in control group 1.3 ± 5.6 fL, p = 0189. 14 The decrease of MCV is influenced by the number of the erythrocyte. MCV is a parameter that sensitive toward changes in erythrocyte when compared with MCH and MCHC to determine the possibility of iron deficiency.…”

Influence of <i>Moringa oleifera</i> leaves on atherogenic lipids and glycaemia evolution in HIV-infected and uninfected malnourished patients

“…Valorization of edible vegetable such as leaves of M. oleifera Lam. (Moringaceae) with high concentration of protein and micronutrients constitute a strategy to combat malnutrition and associated diseases (Idohou-Dossou et al, 2011;Moyo et al, 2011, Tété-Bénissan et al, 2012. Several pharmacological properties are found in M. oleifera leaves which are used in traditional medicine against hyperglycemia (Ndong et al, 2007;Jaiswal et al, 2009), hyperlipidemia, hypercholesterolemia (Naznin et al, 2008;Olugbemi et al, 2010), inflammation (Ndong et al, 2007;Nandave et al, 2009;Atawodi et al, 2010;Moyo et al, 2012), cancer and virus (Anwar et al, 2007).…”