Impact of CPAP treatment for a short period in moderate-to-severe OSAS patients: a randomized double-blind clinical trial

Barros, Jefferson; Rodrigues, Wesley Osvaldo Pradella; Marão, Antônio Carlos; Antunes, Letícia Cláudia de Oliveira; Trindade, Sergio Henrique Kiemle; Weber, Silke Anna Theresa

doi:10.1016/j.bjorl.2020.12.011

Cited by 3 publications

(3 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An altered sleep pattern is an hallmark of untreated OSA and up to 100% of the patients report a subjective sensation of poor sleep quality with a PSQI score well above the cut-off limit [ 24 ]. Treatment with CPAP clearly improves sleep architecture, restoring sleep stages and reducing the number of arousals [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Sleep quality and mental health during the COVID-19 pandemic in patients with severe obstructive sleep apnea

Spicuzza

Mancuso

Campisi

et al. 2022

J Patient Rep Outcomes

View full text Add to dashboard Cite

Background The first wave of the COVID-19 pandemic has produced remarkable effects on the sleep quality and mental status of the general population and more dramatic effects on patients with chronic illness. Patients with obstructive sleep apnea (OSA), already suffering from disordered sleep, might be more susceptible to the effect of the pandemic on their sleep quality and mental health. We therefore performed a case–control study to compare sleep quality, depression and anxiety symptoms reported by patients with severe OSA and age-matched healthy subjects during the first wave of the COVID-19. In June–July 2020 we enrolled a total of 222 patients with severe OSA, all treated with continuous positive airway pressure, and 164 healthy controls. Self-reported sleep quality was assessed using the Pittsburg Sleep Quality Index (PSQI). Symptoms of depression were assessed using the Patient Health Questionnaire module 9 (PHQ-9), while the specific “Coronavirus Anxiety Scale” (CAS) evaluated the level of anxiety. Results Patients with OSA (61% males, 65 ± 9.6 years old, BMI 30.5 ± 3.6) and healthy controls had similar characteristics except for BMI slightly lower in controls. The perceived quality of sleep, referred to the pre-pandemic period, was significantly worse in patients with OSA than in controls. During the pandemic the rate of reported sleep disturbance increased from 54 to 66% in patients with OSA and from 29 to 40% in controls. A high percentage of patients and controls reported symptoms of depression (61% OSA and 65% controls), whereas lower levels of anxiety, similar in the two groups, were observed. In patients with OSA the PSQI score significantly positively correlated with the PHQ-9 score (r2 = 0.81) and the CAS score (r2 = 0.65). Conclusion The rate of reported sleep disturbance in patients with OSA during the first wave of the COVID-19 pandemic is one of the highest evidenced in literature so far. As for the general population, in these patients there is a strict link between the perceived sleep quality and the psychological distress caused by the pandemic. A further deterioration of sleep quality is a fearsome event in the life of these patients who face life-long sleep problems.

show abstract

Section: Discussionmentioning

confidence: 99%

Sleep quality and mental health during the COVID-19 pandemic in patients with severe obstructive sleep apnea

Spicuzza

Mancuso

Campisi

et al. 2022

J Patient Rep Outcomes

View full text Add to dashboard Cite

show abstract

“…Analisando estudos, existe uma correlação entre idade e obesidade, onde o aumento de peso associado a fatores de envelhecimento se torna fatores de risco para AOS, pois o avançar da idade faz com que a força e calibre de vias aéreas tenha diminuição, reduzindo também as atividades musculares (PHYS et al, 2022).…”

Section: Discussionunclassified

“…O estudo de Phys et al, (2022) afirma que a utilização de CPAP ainda que por um curto período de tempo apresenta melhora nos casos de sonolência diurna e na qualidade do sono, melhora a disposição dos indivíduos, além da melhora na função pulmonar. Dos participantes do nosso estudo, 77,2% fizeram uso de ventilação mecânica não invasiva a mais de um ano e desses mais de 96% relataram ter melhora na qualidade do sono após o início do uso.…”

Section: Discussionunclassified

Profile of individuals diagnosed with obstructive sleep apnea who use non-invasive ventilation

Boas,

Clemente,

Rocha Júnior

et al. 2024

OLEL

View full text Add to dashboard Cite

Introduction: Obstructive Sleep Apnea (AOS) can be characterized as a disorder of total or partial obstruction of the upper airways, causing symptoms such as non-restorative sleep, snoring, choking and fatigue associated with cardiovascular diseases, where the VNI uses positive pressures to reduce the work of breathing and increase oxygenation and lung compliance. Objective: To know the profile of CPAP users as a form of treatment for AOS. Methods: This was a descriptive research, carried out in a digital environment, based on validated questionnaires specific for each proposed objective, with data presented as mean and standard deviation or raw data, through SPSS 23.0 with the significance level adopted p<0.05. Results: A total of 82 individuals participated, considering that there were three exclusions for not meeting the inclusion criteria, 79 were evaluated using the PSQI and ESE questionnaires, which evaluated the presence of poor quality sleep without changes in daytime sleepiness of the individuals. Conclusion: it was observed that the use of CPAP for the treatment of OSA improved the users' sleep; even though most of them had a poor quality of sleep, their daytime sleepiness was considered normal.

show abstract

Estudo do impacto na via aérea superior de pacientes com síndrome da apneia obstrutiva do sono submetidos a cirurgia de avanços bimaxilares

Silveira,

Melo,

Ponte

et al. 2024

Cad. Pedagógico

View full text Add to dashboard Cite

As deformidades dento-esqueléticas (DDE) são definidas como desproporções dentárias e faciais decorrentes de alterações de crescimento dos ossos da face. Podem levar à diminuição do espaço da via aérea superior (VAS), contribuindo para o desenvolvimento de distúrbios respiratórios graves, como a síndrome da apneia obstrutiva do sono (SAOS). Este estudo avalia mudanças no espaço aéreo faríngeo dos pacientes portadores da SAOS que foram submetidos a cirurgia de avanço bimaxilar para correção das DDE, a fim de detectar possível aumento da VAS como tratamento cirúrgico definitivo da SAOS. Para a avaliação do espaço aéreo utilizou-se um novo protocolo de delimitação da VAS, onde foram avaliadas tomografias computadorizadas (TC) no pré e pós-operatório da cirurgia ortognática de nove pacientes com perfil facial Classe II que apresentavam a SAOS associada, a fim de mensurar o diâmetro da VAS e o novo posicionamento do osso hioide. Uma vez coletados os valores mensurados, estes foram submetidos ao tratamento estatístico, através do programa SPSS (24.0). Aplicou-se o teste de normalidade de Shapiro-Wilk para averiguar a distribuição dos dados. E o teste t emparelhado para a comparação entre as mensurações no pré e pós-operatório. Observou-se um aumento estatisticamente significativo da VAS no corte sagital (média 0,35; p=0,001) e no corte axial (média 0,51; p=0,001). Já em relação às mudanças de posição do osso hióide, não houve diferenças estatisticamente significativas (p=0,551). A partir dos dados em análise, foi possível concluir que o manejo cirúrgico permitiu um aumento nos diâmetros da VAS e, consequente, redução no índice de apneia e hipopneia (IAH) para níveis próximos à normalidade. Entretanto novos estudos devem ser realizados para um acompanhamento longitudinal desses pacientes.

show abstract

Impact of CPAP treatment for a short period in moderate-to-severe OSAS patients: a randomized double-blind clinical trial

Cited by 3 publications

References 33 publications

Sleep quality and mental health during the COVID-19 pandemic in patients with severe obstructive sleep apnea

Sleep quality and mental health during the COVID-19 pandemic in patients with severe obstructive sleep apnea

Profile of individuals diagnosed with obstructive sleep apnea who use non-invasive ventilation

Estudo do impacto na via aérea superior de pacientes com síndrome da apneia obstrutiva do sono submetidos a cirurgia de avanços bimaxilares

Contact Info

Product

Resources

About