Impact of COVID-19 pandemic on pediatric endoscopy: A multicenter study on behalf of the SIGENP Endoscopy Working Group

Renzo, Sara; Scarallo, Luca; Antoniello, Luca Maria; Bramuzzo, Matteo; Chiaro, Andrea; Cisarò, Fabio; Contini, Anna Chiara Iolanda; Angelis, Gian Luigi De’; Angelis, Paola De; Nardo, Giovanni Di; Felici, Enrico; Iuliano, Silvia; Macchini, Francesco; Mantegazza, Cecilia; Martelossi, Stefano; Oliva, Salvatore; Parrinello, Flavia; Rea, Francesca; Pizzol, Antonio; Romano, Claudio; Russo, G; Sansotta, Naire; Lionetti, Paolo; Dabizzi, Emanuele; Saccomani, Marco Deganello; Toma, Michele Di; Gatti, Simona; Illiceto, M.T.; Isoldi, Sara; Maino, M.; Pellegrino, M.; Strisciuglio, Caterina

doi:10.1016/j.dld.2022.02.010

Cited by 7 publications

(8 citation statements)

References 35 publications

(41 reference statements)

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“…All centers had to suspend or reschedule the GI endoscopies due to the outbreak of SARS-CoV-2 infections, especially since mid-March’20. Therefore, it could be concluded that the effect of COVID-19 on the practice of GI endoscopy in Italian children was important [ 99 ].…”

Section: Celiac Disease In Children During Covid Pandemicmentioning

confidence: 99%

Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic

Ailioaie

Litscher

et al. 2022

IJMS

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Celiac disease (CD) comprises over 1% of the world’s population and is a chronic multisystem immune-mediated condition manifested by digestive and/or extradigestive symptoms caused by food intake of gluten. This review looked at the risk of children diagnosed with CD developing SARS-CoV-2 infection and possible severe forms of COVID-19. A better understanding of the interaction and effects of SARS-CoV-2 infection in CD is very important, as is the role of environmental and genetic factors, but especially the molecular mechanisms involved in modulating intestinal permeability with impact on autoimmunity. CD inspired the testing of a zonulin antagonist for the fulminant form of multisystem inflammatory syndrome in children (MIS-C) and paved the way for the discovery of new molecules to regulate the small intestine barrier function and immune responses. Original published works on COVID-19 and CD, new data and points of view have been analyzed because this dangerous virus SARS-CoV-2 is still here and yet influencing our lives. Medical science continues to focus on all uncertainties triggered by SARS-CoV-2 infection and its consequences, including in CD. Although the COVID-19 pandemic seems to be gradually extinguishing, there is a wealth of information and knowledge gained over the last two years and important life lessons to analyze, as well as relevant conclusions to be drawn to deal with future pandemics. Zonulin is being studied extensively in immunoengineering as an adjuvant to improving the absorption of new drugs and oral vaccines.

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Section: Celiac Disease In Children During Covid Pandemicmentioning

confidence: 99%

Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic

Ailioaie

Litscher

et al. 2022

IJMS

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“…During the peak of COVID-19, diagnostic endoscopies for suspected IBD fell by 15.5%, while procedures to assess mucosal healing decreased by 48.3%, according to a recent survey conducted by the SIGENP Endoscopy Working Group (see below) [ 22 ]. Nevertheless, the SIGENP IBD Working Group recommended not deferring endoscopic procedures in cases of confirmation of new diagnoses, severe acute flares, or the occurrence of complications (Table 1 ) [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…Upper digestive tract endoscopy can cause airborne transmission by inducing coughing, gagging, and retching, whereas colonoscopy can result in the passage of flatus and pathogen-carrying liquid stools. In December 2020, the SIGENP Endoscopy Working Group conducted a web-based survey among 24 Italian pediatric centers that perform digestive endoscopies [ 22 ]. The purpose of this study was to assess the impact of COVID-19 on procedural volumes, indications, healthcare provider safety perceptions, and waiting times for pediatric endoscopies.…”

Section: Introductionmentioning

confidence: 99%

“…The purpose of this study was to assess the impact of COVID-19 on procedural volumes, indications, healthcare provider safety perceptions, and waiting times for pediatric endoscopies. Between 2019 and 2020, there was a 37.2% decrease in digestive endoscopies, with a substantial decrease in the median number of procedures (111 vs 57, p < 0.001) [ 22 ]. The median number of procedures performed either for new diagnosis or follow-up declined significantly in 2020 (63 vs 36, p < 0.001 and 42 vs 21, p < 0.001, respectively) [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

“…Between 2019 and 2020, there was a 37.2% decrease in digestive endoscopies, with a substantial decrease in the median number of procedures (111 vs 57, p < 0.001) [ 22 ]. The median number of procedures performed either for new diagnosis or follow-up declined significantly in 2020 (63 vs 36, p < 0.001 and 42 vs 21, p < 0.001, respectively) [ 22 ]. While endoscopies for new diagnoses of celiac disease, functional gastrointestinal disorders (FGIDs), suspected Helicobacter pylori infection, eosinophilic gastroenteropathy, or to exclude FGIDs were significantly reduced, only a minor drop was noted for IBD new diagnoses [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pediatric Gastroenterology and Hepatology in Italy before and after the COVID-19: Lessons learned and management changes by SIGENP

et al. 2023

Self Cite

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AbstractAround the world, the 2019 Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised serious public health problems and major medical challenges. The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) published several papers on the impact of COVID-19 on the current management, diagnosis, and treatment of acute and chronic gastrointestinal, hepatic, immune-mediated, and functional disorders. The present article summarizes the most relevant SIGENP reports and consensus during and after the peak of the COVID-19 outbreak, including the diagnosis and treatment of inflammatory bowel disease (IBD), indications and timing of digestive endoscopy, and insights into the novel hepatitis.

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Mobile health technology in pediatric EGD quality indicators assessment: results from a national program of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition

Norsa,

Morotti,

Mantegazza

et al. 2024

Gastrointestinal Endoscopy

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Impact of COVID-19 pandemic on pediatric endoscopy: A multicenter study on behalf of the SIGENP Endoscopy Working Group

Cited by 7 publications

References 35 publications

Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic

Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic

Pediatric Gastroenterology and Hepatology in Italy before and after the COVID-19: Lessons learned and management changes by SIGENP

Mobile health technology in pediatric EGD quality indicators assessment: results from a national program of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition

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