Impact of COVID-19 Pandemic on Ovarian Cancer Management: Adjusting to the New Normal

Jacome, Lizbeth Soto; Deshmukh, Sachin Kumar; Thulasiraman, Padmamalini; Holliday, Nicolette; Singh, Seema

doi:10.2147/cmar.s287152

Cited by 27 publications

(30 citation statements)

References 53 publications

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“…Several different strategies were adopted to try and deal with these problems. Risk−benefit analyses were typically conducted on a patient-by-patient basis, with treatments being postponed or withdrawn where the benefit offered by therapy was marginal [ 27 , 28 , 29 ]. Where possible, chemotherapy regimens were switched to the oral route to reduce the need for patients to attend hospital where they would run the risk of acquiring SARS-CoV-2 [ 30 ].…”

Section: Impact Of the Management Of Patients With Cancermentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

Ali

Riches

2021

Cancers

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The coronavirus disease 2019 (COVID-19) pandemic has caused considerable global disruption to clinical practice. This article will review the impact that the pandemic has had on oncology clinical trials. It will assess the effect of the COVID-19 situation on the initial presentation and investigation of patients with suspected cancer. It will also review the impact of the pandemic on the subsequent management of cancer patients, and how clinical trial approval, recruitment, and conduct were affected during the pandemic. An intriguing aspect of the pandemic is that clinical trials investigating treatments for COVID-19 and vaccinations against the causative virus, SARS-CoV-2, have been approved and conducted at an unprecedented speed. In light of this, this review will also discuss the potential that this enhanced regulatory environment could have on the running of oncology clinical trials in the future.

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Section: Impact Of the Management Of Patients With Cancermentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

Ali

Riches

2021

Cancers

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“…Several different strategies were adopted to try and deal with these problems. Risk-benefit analyses were typically conducted on a patient-by-patient basis with treatments being postponed or withdrawn where the benefit offered by therapy was marginal [23][24][25]. Where possible, chemotherapy regimens were switched to the oral route to reduce the need for patients to attend hospital where they would run the risk of acquiring SARS-CoV-2 [26].…”

Section: Impact Of the Management Of Patients With Cancermentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

Ali¹,

Riches²

2021

Preprint

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The coronavirus disease 2019 (COVID-19) pandemic has caused considerable global disruption to clinical practice. This article will review the impact that the pandemic has had on oncology clinical trials. It will assess the effect of the COVID-19 situation on the initial presentation and investigation of patients with suspected cancer. It will also discuss the impact of the pandemic on the subsequent management of cancer patients and how clinical trial approval, recruitment and conduct were affected during the pandemic. An intriguing aspect of the pandemic is that clinical trials investigating treatments for COVID-19 and vaccinations against the causative virus, SARS-CoV-2, have been approved and conducted at unprecedented speed. In light of this, this re-view will also discuss the potential that this enhanced regulatory environment could have on the running of oncology clinical trials in the future.

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“…Many cancer patients experience additional stressors, such as transportation restrictions or economic strains [ 12 ]. In addition, due to the need to protect patients and staff from the COVID-19 contagion, the procedures of hospital visits changed, such as the use of masks, temperature checks, social distancing, and not being escorted by a caregiver [ 1 ]. All this adds to the pre-existing psychological burden of coping with cancer, its treatments, and its physical and mental consequences [ 13 , 14 ] and can result in high levels of various emotional and mental symptoms [ 1 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Cancer patients attending treatment during COVID-19: intolerance of uncertainty and psychological distress

et al. 2022

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Purpose The COVID-19 pandemic presents specific challenges for cancer patients attending oncology treatment. Using a mixed-methods design (convergent parallel design), we aimed to assess the experience, perceptions, and reactions of cancer patients during the COVID-19 pandemic. Methods Participants were cancer patients receiving treatment at the hospital during the pandemic (July to August 2020). In study 1, 95 participants filled out a questionnaire measuring COVID-19 experiences and perceptions, psychological distress, and intolerance of uncertainty. In study 2, in-depth interviews were conducted with 10 cancer patients, probing their experience during the COVID-19 period. Results Most participants experienced the COVID-19 pandemic as a major threat that would affect future health, most attended all or most of their scheduled treatments, and their mean level of psychological distress was low. A mild decrease in social support was reported, and remote contacts and support from the community had not compensated for decreased person-to person contacts. In addition, intolerance of uncertainty was related to higher psychological distress, which was partially mediated by perceptions of threat. The analysis of in-depth interviews strengthened the quantitative findings by elucidating the experience of fear of contagion alongside determination to continue treatment. Conclusions and Implications for Cancer Survivors The mixed-methods design enabled us to examine the responses of cancer patients attending treatment. The findings suggest that in times of extreme uncertainty such as COVID-19, health experts need to screen cancer patients and survivors for emotional and instrumental support needs and identify patients and survivors with high intolerance of uncertainty as a risk factor for psychological distress.

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Impact of COVID-19 Pandemic on Ovarian Cancer Management: Adjusting to the New Normal

Cited by 27 publications

References 53 publications

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

The Impact of the COVID-19 Pandemic on Oncology Care and Clinical Trials

Cancer patients attending treatment during COVID-19: intolerance of uncertainty and psychological distress

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