Impact of COPD on Postoperative Outcomes

Impact of Airflow Limitation on Comorbidities and Postoperative Complications in Patients Undergoing Thoracic Surgery: A Retrospective Observational Study

“…They reported that patients with COPD had higher rates of other comorbidities and significantly higher rates of postoperative complications, including prolonged hospitalization and higher mortality. 4) Similar findings have been reported by other investigators, although not yet in Japan. Accordingly, we retrospectively assessed the frequency of airflow limitation, and the relationships between airflow limitation and preoperative comorbidities and postoperative complications, in patients who underwent thoracic surgery (excluding intra-thoracic cardiovascular surgery) under the care of the Department of General Thoracic Surgery, Juntendo University Hospital, Japan.…”

Prevalence and risk factors for postoperative pulmonary complications after lung cancer surgery in patients with early stage of COPD

“…Previously published studies 8,[28][29][30][31] have shown COPD to be a well-known risk factor for PPCs, probably because of impairment of gas exchange and mucociliary clearance of aspirated bacteria. However, no prior studies have been conducted in patients with relatively preserved lung function.…”

“…Other major significant clinical and economic impacts of PPCs include a prolonged hospital stay and the need for admission to the intensive care unit. [7][8][9] Many previous studies 8, [10][11][12][13][14][15][16][17][18][19][20][21][22] have suggested that the patient's health status, age, sex, body mass index (BMI), history of smoking, chronic pulmonary disease, and preoperative pulmonary function tests (PFTs) are predictors of PPC. However, they have not been adopted widely in clinical practice, because none of them has been proven to be a sufficiently reliable predictor of PPCs, 8,[10][11][12][13][14][15][16][17][18][19][20][21][22] and further controlled trials are required before a consensus regarding these predictors can be established.…”

Airflow limitation severity and post‐operative pulmonary complications following extra‐pulmonary surgery in COPD patients

“…[8][9][10] COPD is characterized by chronic inflammation of the airways and lung tissue as a result of exposure to inhaled irritants such as smoking. 1 Chronic inflammation causes the destruction of lung parenchyma and the narrowing of small airways, leading to ventilation-perfusion mismatching and impaired gas exchange.…”

“…7 COPD is associated with increased risk of PPC, inhospital mortality and length of hospital stay after surgery. [8][9][10] Indeed, some risk factors for COPD, 1 such as smoking, age and poor general condition, are also associated with the development of PPC. 11,12 While COPD patients are at higher risk of PPC, the impact of airflow limitation severity on PPC after extrapulmonary surgery in COPD patients has not been adequately investigated.…”