Impact of contrast-enhanced ultrasound in the study of hepatic artery hypoperfusion shortly after liver transplantation: contribution to the diagnosis of artery steal syndrome
Abstract:• CEUS is useful in the diagnostic work-up shortly after liver transplant • CEUS identifies the hepatic artery thrombosis with reliability • There is little information about DUS and CEUS findings in the ASS • DUS and CEUS offer functional information useful in the diagnosis of ASS.
“…Contrast material-enhanced US has proven to be an important tool in assessment of the graft vasculature as well as the liver parenchyma and may obviate angiography and cross-sectional imaging methods (21,22). Nevertheless, it is not yet widely used in clinical practice for standard evaluation after liver transplant.…”
Liver transplant is considered to be the last-resort treatment approach for pediatric patients with end-stage liver disease. Despite the remarkable advance in survival rates, liver transplant remains an intricate surgery with significant morbidity and mortality. Early diagnosis of complications is crucial for patient survival but is challenging given the lack of specificity in clinical presentation. Knowledge of the liver and vascular anatomy of the donor and the recipient or recipients before surgery is also important to avoid complications. In this framework, radiologists play a pivotal role on the multidisciplinary team in both pre- and postoperative scenarios by providing a road map to guide the surgery and by assisting in diagnosis of complications. The most common complications after liver transplant are (a) vascular, including the hepatic artery, portal vein, hepatic veins, and inferior vena cava; (b) biliary; (c) parenchymal; (d) perihepatic; and (e) neoplastic. The authors review surgical techniques, the role of each imaging modality, normal posttransplant imaging features, types of complications after liver transplant, and information required in the radiology report that is critical to patient care. They present an algorithm for an imaging approach for pediatric patients after liver transplant and describe key points that should be included in radiologic reports in the pre- and postoperative settings. Online supplemental material is available for this article. RSNA, 2017.
“…Contrast material-enhanced US has proven to be an important tool in assessment of the graft vasculature as well as the liver parenchyma and may obviate angiography and cross-sectional imaging methods (21,22). Nevertheless, it is not yet widely used in clinical practice for standard evaluation after liver transplant.…”
Liver transplant is considered to be the last-resort treatment approach for pediatric patients with end-stage liver disease. Despite the remarkable advance in survival rates, liver transplant remains an intricate surgery with significant morbidity and mortality. Early diagnosis of complications is crucial for patient survival but is challenging given the lack of specificity in clinical presentation. Knowledge of the liver and vascular anatomy of the donor and the recipient or recipients before surgery is also important to avoid complications. In this framework, radiologists play a pivotal role on the multidisciplinary team in both pre- and postoperative scenarios by providing a road map to guide the surgery and by assisting in diagnosis of complications. The most common complications after liver transplant are (a) vascular, including the hepatic artery, portal vein, hepatic veins, and inferior vena cava; (b) biliary; (c) parenchymal; (d) perihepatic; and (e) neoplastic. The authors review surgical techniques, the role of each imaging modality, normal posttransplant imaging features, types of complications after liver transplant, and information required in the radiology report that is critical to patient care. They present an algorithm for an imaging approach for pediatric patients after liver transplant and describe key points that should be included in radiologic reports in the pre- and postoperative settings. Online supplemental material is available for this article. RSNA, 2017.
“…The presence of a hepatic arterial diastolic reversal waveform or a high RI has not been reported in these conditions. It has been reported that splenic steal syndrome can cause a substantial decrease in blood flow and may also lead to the misdiagnosis of thrombosis on Doppler sonography 6 , 24 , 25 . However, none of our splenic steal syndrome cases were reported as being misdiagnosed as hepatic artery thrombosis cases on Doppler sonography because the hepatic artery was visualized on Doppler sonography in all patients.…”
Section: Discussionmentioning
confidence: 55%
“…Therefore, the number of Doppler sonograms obtained varied among patients, which may have affected our results. Contrast‐enhanced sonography has been used to detect vascular complications after orthotopic liver transplantation and has proved to be useful in identifying hepatic artery thrombosis and splenic steal syndrome 25 , 26 . However, ultrasound contrast agents have not been applied clinically in this country.…”
“…Some included studies restricted the interpretation protocol in order to reduce the chance of a misdiagnosis. CEUS was not performed if there were no available trained radiology staff in the study of Garcacriado (25). More than one experienced examiner was involved in analyzing the CEUS scan in order to avoid misreading in the study performed by Rennert and Zheng (32,34).…”
Section: Discussionmentioning
confidence: 99%
“…Relevant data extracted from all 13 studies are summarized in table 1 (23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35). Only two studies involved more than 100 cases for CEUS evaluation.…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.