Impact of Computer-Aided Detection in a Regional Screening Mammography Program

Abstract

Increased detection rate, younger age at diagnosis, and significantly earlier stage of invasive cancer detection are consistent with a positive screening impact of CAD. Audit results were positive but generally not statistically significant due to sample size limitations. Our findings support the hypothesis that screening with CAD significantly improves detection of the specific cancer morphologies that CAD algorithms were designed to detect.

CAD in mammography: lesion-level versus case-level analysis of the effects of prompts on human decisions

“…This checked for the satisfaction of several "consistency rules". For example, if MAOI A had been marked by reader 1, the record for this MAOI should also contain information about the type of abnormality (mass or calcification) and the level of suspicion (1)(2)(3)(4)(5) assigned by the reader to that MAOI. The violation of this "consistency rule" would indicate incomplete or erroneous data entry.…”

“…At best, the available evidence indicates highly variable results between different settings, with some controversy (see reviews in [1] and [2]). Whereas some studies show that the introduction of CAD results in a significant increase in cancer detection [3,4], other studies show negligible effects [5,6], inferior to the benefits of double reading [7]. A recent study has shown harmful effects of CAD.…”

Digital mammography: what do we and what don’t we know?

“…Although mammography CAD systems have received wide-spread adoption in the US, where there is additional reimbursement for the use of CAD, the clinical value of CAD is still being debated [63]. Several clinical studies have demonstrated that by using CAD more and smaller cancers can be detected, usually at the expense of a slightly higher recall rate [64][65][66]. The usefulness of CAD will vary with the mammography experience of the reader, and thorough training in the use of the CAD system will improve results [63].…”

Microcalcification Detection in Digitized Mammograms: A Neurobiologically-Inspired Approach

“…Furthermore, in chest radiography and thoracic CT, CAD schemes include the detection and differential diagnosis of lung nodules, interstitial lung diseases, and the detection of cardiomegaly, pneumothorax and interval changes (Doi, 2007). Researchers have reported an important reduction in the mean age of patients at the time of detection when CAD was used along with the increase in the detection rates of breast cancer (Cupples et al, 2005), similar results were achieved on the detection rates of lung cancer, colon diseases, intracranial aneurysms, among others (Doi, 2007).…”