Impact of competitive flow on wall shear stress in coronary surgery: computational fluid dynamics of a LIMA–LAD model

Abstract

Graft flow is highly dependent on the degree of competitive flow. High competitive flow was found to produce unfavourable WSS consistent with endothelial dysfunction and subsequent graft narrowing and failure. Partial competitive flow, however, may be better tolerated as it was found to be similar to the ideal condition of no competitive flow.

Computation of hemodynamics in the left coronary artery with variable angulations

“…Later reports further confirmed these early observations (Katritsis et al, 2007;Nordgaard et al, 2010). Katritsis et al (2007) investigated the WSS oscillations based on the simulated artery bifurcation model comprising a straight tube, and their results showed that low wall shear stress occurred in the bifurcation locations.…”

“…Katritsis et al (2007) investigated the WSS oscillations based on the simulated artery bifurcation model comprising a straight tube, and their results showed that low wall shear stress occurred in the bifurcation locations. Nordgaard et al (2010) in their recent report studied WSS in the remodeled left coronary artery and stated that low WSS was found in regions of low flow rate. Again, our analysis is consistent with these observations.…”

“…Early hemodynamic analysis of coronary artery disease performed using computational fluid dynamic (CFD) techniques has been typically performed using one of two approaches, they were based on either simulated models or realistic coronary artery geometry simulations (Lim and Kern, 2005;Katritsis et al, 2007;Shanmugavelayudam et al, 2010;Wellnhofer et al, 2010;Nordgaard et al, 2010). As far as we know, no systematic studies have been performed hitherto that relate bifurcation angles to flow instabilities predisposing to the formation of atherosclerotic lesions.…”

Artery Length Sensitivity in Patient-Specific Cerebral Aneurysm Simulations

“…The OSI parameter was defined as in Ku et al 20 A maximum value of 0.5, shows that WSS ¡ is fully changing the direction during the cardiac cycle, which usually describes a complex pulsatile flow. 21 We analyzed the velocity and WSS parameters at peak systole in the fourth cardiac cycle and the OSI during the entire fourth cycle. We chose the peak systole for the error analysis because of the larger errors compared with other time points in the cardiac cycle.…”

Numerical analysis of Venous External Scaffolding Technology for Saphenous Vein Grafts

“…Computational fluid dynamics (CFD) is the most common method to explore complex flow mechanics and to investigate the WSS distribution in vessels, including coronary arteries and bypass grafts (Nordgaard et al, 2010). Combining various topographic and anatomic features with real and theoretical hemodynamic conditions using computer based modeling provides a mechanism to investigate these potential interactions (Ricotta et al, 2008).…”