Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia

Al-Qadheeb, Nada S.; Almubayedh, Hanine; AlBadrani, Sarah; Salam, Abdul; AlOmar, Mukhtar; AlAswad, Ahmed; Almualim, Mohammed; Qamariat, Zahra AL; Alhubail, Rasheed

doi:10.1016/j.clinpr.2023.100229

Cited by 2 publications

(2 citation statements)

References 37 publications

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“…The heightened healthcare expenses could potentially be attributed to activities like the screening for novel coronaviruses or the inappropriate use of antibiotics in the context of the COVID-19 pandemic. 20,37,38 To enhance the emergency care process during the pandemic, it is important to avoid unnecessary screenings and the excessive use of antibiotics driven by panic. This research comprises a retrospective cohort study conducted at a single medical center, without the inclusion of extensive statistical outcomes from multiple centers and a large participant pool.…”

Section: Dovepressmentioning

confidence: 99%

“…3,16,18,19 This trend contributed to elevated rates of severity, mortality, and medical resource consumption among elderly patients with a history of chronic ailments. 20 Following the emergence of the COVID-19 pandemic, China implemented a strategy centered on societal measures to prevent the spread of the virus. This approach involved targeted identification and treatment of individuals suspected or confirmed to have the virus.…”

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confidence: 99%

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Effects of the Novel Coronavirus Pandemic on the Identification and Care of Critically Ill Emergency Patients Not Infected with COVID-19

Zhu,

Li,

et al. 2023

RMHP

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To clarify variations of diagnosis and treatment in the emergency care of critically ill patients not infected with novel coronavirus prior to and amidst the COVID-19 pandemic. Methods: A retrospective cohort study was conducted to compare and analyze the diagnosis and treatment data of critically ill patients with non-COVID-19 infection who were admitted to the emergency department of the Fourth Medical Center of Chinese PLA General Hospital from January 2019 to November 2022. The variations in emergency care of the pandemic were summarized, and the influence of the pandemic on emergency care was assessed. Results: A total of 6634 critically ill patients with non-COVID-19 infection were included in this study. These patients were elderly, high incidence of chronic diseases, and extended emergency duration during the pandemic. Notably, the proportion of patients requiring intensive care was twofold higher compared to the period before the pandemic. Throughout the pandemic, patients experienced prolonged emergency durations, increased overall costs and daily expenses per patient. Further investigation revealed that elderly patients exhibited worse medical conditions, requiring lengthier emergency treatment and incurring escalated healthcare expenses. However, the presence of pre-existing chronic diseases did not appear to influence disease severity, nor extended emergency durations or heightened healthcare expenditures. Irrespective of the pandemic phase-be it short-term, medium-term, or long-term emergency care-greater healthcare spending was necessary. Conclusion:There was no difference in the disease spectrum of emergency critical ill patients with non-COVID-19 infection prior to and amidst the COVID-19 pandemic, nor the duration and expenditure in prior chronic illness patients. However, the disease severity and emergency duration have led to an increase in the total cost and economic intensity of emergency care for all patients during the epidemic. Especially, elderly patients required longer emergency duration, greater healthcare spending, and more inpatient medical resources than usual.

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Section: Dovepressmentioning

confidence: 99%

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confidence: 99%

Effects of the Novel Coronavirus Pandemic on the Identification and Care of Critically Ill Emergency Patients Not Infected with COVID-19

Zhu,

Li,

et al. 2023

RMHP

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Prevalence and impact of comorbidities in hospitalized patients with COVID-19: a study from Saudi Arabia

alqahtani,

Al Saglan,

AlShehry

et al. 2023

Egypt J Bronchol

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Background In this study, we aimed to address the prevalence of comorbidities and their impact on the outcomes of hospitalized COVID-19 patients admitted to a large tertiary Saudi Arabian hospital. Methods This is a retrospective study that included all adults with COVID‑19 admitted to a large tertiary Saudi Arabian hospital, between January 1, 2021, and September 30, 2022. The study outcomes were the prevalence of comorbidities among hospitalized COVID-19 patients and the effects of these comorbidities on all‑cause hospital mortality. Results A total of 1118 /1853 (60.3%) patients had one or more comorbidities. The most prevalent comorbidity was diabetes mellitus (48.5%), followed by hypertension (12.5%), and chronic renal disease (10.3%). Age (OR 3.032 (95% CI 0.006 – 0.029, p = 0.002), clinical status (8.194, 0.0350 – 0.709, p < 0.001), the presence (versus absence) of comorbidities (3.167, 0.042—0.233, p = 0.002), the number of comorbidities (2.972, 0.027 – 0.133, p = 0.003), and the 4C score (2.894, 0.010 – 0.054, p = 0.004), were independent significant predictors of mortality. Conclusions A total of 60.3% of hospitalized COVID-19 patients had one or more comorbidities, the most prevalent of which were diabetes mellitus, hypertension, and chronic renal disease. The presence and the number of comorbidities, but not the individual ones, together with age, clinical status at admission, and the 4C mortality score were significant independent predictors of mortality.

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Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia

Cited by 2 publications

References 37 publications

Effects of the Novel Coronavirus Pandemic on the Identification and Care of Critically Ill Emergency Patients Not Infected with COVID-19

Effects of the Novel Coronavirus Pandemic on the Identification and Care of Critically Ill Emergency Patients Not Infected with COVID-19

Prevalence and impact of comorbidities in hospitalized patients with COVID-19: a study from Saudi Arabia

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