Impact of collateral circulation in a patient with chronic coronary occlusion

Refined metabolite profiling in the collateral circulation of chronic total occlusion of coronary arteries: Insights from a metabolomics investigation

“…Literature reports have demonstrated a strong association between thiol levels, uric acid/albumin ratio, and inflammatory markers in stable CHD patients with established CCC [ [20] , [21] , [22] ]. Additionally, adrenaline plays a crucial role in the process of CCC formation [ 23 ].…”

“…The establishment of CCC in cases of CTO is influenced by various factors, and the specific mechanisms remain unclear [ [6] , [7] , [8] , [9] ]. We speculated that regulatory substances present in the local blood of CCC may promote capillary neovascularization.…”