“…Our meta-analysis revealed no overall signifcant increase in the concentration of anthocyanin and phenolics due to CT; however, many individual studies indicated a positive efect of CT on berry anthocyanin and phenolic concentration. Increases in anthocyanins were observed in studies performed in various wine regions that considered multiple varieties, including Nebbiolo [97], Tempranillo [51,[98][99][100][101], Syrah [100,102], Sangiovese [15], Grenache [91], Pinot Noir [10,34,46,103], Cabernet Sauvignon [27,32,39,46,104], Merlot [31], Malbec [36], Refosco [105], Tannat [92], and Cabernet Franc [8,104]. Te observed increases in grape and wine anthocyanin concentration might be determined by the increases in sugars determined by CT. Anthocyanin and sugar accumulation at the onset of ripening are strongly related [106]; however, uncoupling efects between anthocyanin and sugars may be observed during ripening when grapes are subjected to environmental stresses, such as drought or heat stress [107][108][109].…”