Impact of clinical staging and demographic data (age and sex) on response to treatment and survival of chronic lymphocytic leukemia patients in Kurdistan Region of Iraq

Rashid, BryarSabah; Jalal, SanaD; Yassin, AhmedK; Hassan, KawaM; Mohamed, ZekiA; Ahmed, ZhalaO; Mahmood, TavanI; Shamoon, RawandP; Mustafa, ShokhanM; Karam, MarwaNadhim; Abdullah, DanaA; Mohammad, ShlanS; Abdulrahman, LaraL; Yousif, Rozh-hatA; Abdulla, BasilK; Mohammed, NawsherwanS; Getta, HishamA; Polus, RananK; Numan, GhanimS

doi:10.4103/ijh.ijh_11_21

Cited by 2 publications

(1 citation statement)

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“…Besides, non-Hispanic Caucasians and the female gender had more favourable survival rates than the other (3) . To the best of our knowledge, the studies which have been done in Kurdistan Region/ Iraq on the same topic are as follows: one study found a 3-year survival rate of 71.98% for children (7) , another study found a 5-year survival rate of 49% for adults (8) , and another study focused on chronic lymphocytic leukaemia (CLL) (9) . Also, we found another study in the Kurdistan Province of Iran that focused on adult and pediatric ALL and acute myeloid leukaemia (AML); they found a 5-year survival rate of 83% in the children (10) .…”

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confidence: 99%

Survival and Demographic Features in Children With Acute Lymphoblastic Leukemia

Mohammed,

Salih,

Abdalla

2023

JSMC

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BackgroundAcute lymphoblastic leukemia (ALL) is a malignant blood cancer of T-cell or B-cell lineages. ObjectivesThe aim was to obtain local data on the demographic features of pediatric patients with ALL and correlate them with a five-year survival rate. Patients and MethodsA retrospective cohort study was performed on 94 ALL pediatric patients aged 1-14 admitted to the Hiwa Hospital from 2014 to 2016. The diagnostic methods, clinical features, and histological and biochemical parameters were reviewed. Further, a five-year survival rate was assessed. ResultsThe mean±SD (standard deviation) of patients’ ages at diagnosis was 5.2±3.1 years, ranging from 1 to 14. Males were 57.4%, and females were 42.6%, with a male-to-female ratio of (1.35:1). Most patients (61.7%) suffered from the low-risk (A), and the majority of patients (90.4%) were in remission. The five-year survival rate was 80.9%. The associations of age groups, gender, white blood cell (WBC) groups, risk groups, and post-induction status with a five-year survival rate were insignificant (p-values of >.05). The association of immunophenotyping with the five-year survival rate was statistically significant (p-value = .014). ConclusionThe 5-year survival rate was 80.9% in the current study. Further, although the frequency of some characteristics was more than others, the associations of the patient characteristics with the five-year survival rates were insignificant, except for the association of the five-year survival rate with immunophenotyping which was significant.

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