Impact of chrono-radiotherapy on the prognosis and treatment-related toxicity in patients with locally advanced nasopharyngeal carcinoma: A multicenter propensity-matched study

Abstract

Supplementary Figure 1. CONSORT diagram of the study. Abbreviations: LA-NPC -locally advanced nasopharyngeal carcinoma; CRT -chemoradiotherapy. KPS -Karnofsky performance status. Supplementary Figure 2. Kaplan-Meier curves illustrate the survival of patients in DAY/NIGHT cohorts before PSM. (a) overall survival, (b) progression-free survival, (c) locoregional recurrencefree survival and (d) distant metastasis-free survival. Supplementary Figure 3. Kaplan-Meier curves illustrate the survival of patients in SUMMER/WINTER cohorts before PSM. (a) overall survival, (b) progression-free survival, (c) locoregional recurrence-free survival and (d) distant metastasis-free survival.Supplementary Table .1 Patient Characteristics in the entire cohort. Variable Distribution Age-year* 46.27±11.71 Male/Female 258(72.7%)/97(2.3%) BMI* 22.83±11.3.43 Family History 25(7.0) Smoke 134(37.7) Diabetes 19(5.4) Hypertension 37(10.4) cT stage 1 21(5.9%) 2 85(23.9%)