Impact of Chisan® (ADAPT-232) on the quality-of-life and its efficacy as an adjuvant in the treatment of acute non-specific pneumonia

Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine

“…In a double-blind, parallel-group, randomised (simple randomisation), pilot study, Chisan ® (ADAPT-232; Swedish Herbal Institute, Askloster, Sweden), a standardised fixed combination of extracts of Rhodiola rosea, Schisandra chinensis and Eleutherococcus senticosus, was evaluated for its efficacy as an adjuvant therapy for the improvement of the quality-of-life and recovery period of patients suffering from acute non-specific pneumonia and receiving a standard treatment (Narimanian et al, 2005). Sixty patients (males and females; 18-65 years old) received a standard treatment with cephazoline, bromhexine, and theophylline: in addition, one group of 30 patients received Chisan mixture whilst the second group of 30 patients received a placebo, each medication being taken twice daily from the beginning of the study for 10-15 days.…”

“…;Lupandin (1990a, b);Narimanian et al (2005);Negoda et al (1999);Roslyakova et al (2000);Vezirishvili et al (1999) Stimulation of CNSYefimov and Vlasova (1945); Markova and Samoilova (1954) Improves impaired visual function and vision in darknessGalochkina (1948);Golovin and Golovina (1963);Lebedev (1971a, b);Minejeva and Svindyukova (1968);Sinovich and Akhmetova (1958);Sosnova et al (1984);Trusov (1953Trusov ( , 1958a,b) Local anti-inflammatory effectLupandin (1966) Improves quality of life Narimanian et al (2005) Prevention of chemotherapy-induced immunosuppression in cancer Kormosh et al (2006) Radioprotection Fedorova et al (1994) Gastric hyper-and hypo-secretion, chronic gastritis, stomach and duodenal ulcers…”

Potential of a polyherbal drug to prevent antimicrobial resistance in bacteria to antibiotics

“…As development of antibiotic resistance is dependent on persistence of antibiotic for prolonged period in the milk, the outcome of the present study may be a used as a strategy for reducing the development of antimicrobial resistance. In a similar kind of experiment earlier it was observed that mean duration of treatment for pneumonia with antibiotics was reduced significantly with the use of Chisan®, a polyherbal drug 30 . Moreover, dosing interval of an antibacterial drug in mastitis should be based on dispositional profile and persistence of its major active metabolite in milk when the active antibacterial metabolite primarily excretes through milk.…”

Rhodiola (Rhodiola spp.): An Evidence-Based Systematic Review by the Natural Standard Research Collaboration

“…60 Sixty patients with nonspecific pneumonia were included. Patients were excluded if they were intolerant to any of the medications or herbal products used, if the patients used other medications, or if the patients were severely underweight or overweight.…”