Impact of Change in Lifestyle and Exercise on Cognitive Function in Patients With Rheumatoid Arthritis: A Systematic Review

Abstract

Rheumatoid arthritis (RA) is a chronic destructive type of arthritis. It has a high prevalence in females as compared to the male population globally. It mainly affects the synovium of peripheral joints and leads to the destruction of joints with time. Patients with RA usually have a high burden of inflammation which may lead to certain physical disabilities and debilitating effects on mental health and cognitive ability. The question we investigated here in this systematic review is how changing lifestyles and increasing exercise or physical activities affects one's cognitive abilities. This article adheres to preferred reporting items for systematic review and meta-analyses (PRISMA) guidelines. We used different databases such as PubMed, MEDLINE, and ScienceDirect to find relevant articles. To ensure the quality of the finally selected 12 studies, we followed different quality appraisal tools.Based on our review, we found out that increasing physical activities and aerobic exercises positively increase overall well-being and decrease the inflammatory load, which will ultimately positively impact cognitive function in this subgroup of patients. We also discover certain key players affecting motivation, perception, and adherence to physical activities. We encourage future studies to be done on this topic to help in increasing quality of life and increasing independence in this group of patients. Counseling and addressing patient concerns are very important and keep disease activity well controlled so that physical activities become feasible.

Exploring the significance of microbiota metabolites in rheumatoid arthritis: uncovering their contribution from disease development to biomarker potential

“…Lifestyle choices, including smoking, physical activity levels, and stress, can influence RA susceptibility and disease outcomes [249]. Smoking, in particular, has been identified as a significant environmental risk factor for RA development, contributing to immune dysregulation and joint inflammation [249].…”

“…Lifestyle choices, including smoking, physical activity levels, and stress, can influence RA susceptibility and disease outcomes [249]. Smoking, in particular, has been identified as a significant environmental risk factor for RA development, contributing to immune dysregulation and joint inflammation [249]. Conversely, regular exercise and stress management techniques may have beneficial effects on immune function and disease progression in RA patients [250].…”

Artrite Reumatoide Em Vídeos Percepção De Estudantes De Saúde Antes E Após a Exibição De Vídeos Sobre a Doença

“…O estilo de vida do indivíduo é um fator de risco modificável e determinante para o manejo da artrite reumatoide. A prática de atividade física é de grande relevância na saúde do paciente, desde que a atividade da doença esteja bem controlada, o exercício físico auxilia no processo de desinflamação, na diminuição do risco de complicações cardiovasculares e na redução do risco de desenvolvimento de deficiências cognitivas (Akram et al, 2021).…”

Effects of nonsurgical periodontal therapy in patients with rheumatoid arthritis: a prospective before and after study

“…In contrast, recent data indicate that the global prevalence of RA is between 0.40-1%, with a similar prevalence in Colombia (0.52%) 4,5 . Both diseases are of great interest as they have been found to impact the quality of life of people negatively 6,7 . In the last decade, evidence has emerged suggesting an association between the two conditions [8][9][10] .…”

“…En contraste, datos recientes indican que la prevalencia global de AR se encuentra entre 0.40-1%, con una prevalencia similar en Colombia (0.52%) 4 , 5 . Ambas enfermedades son de gran interés ya que se ha encontrado que afectan negativamente la calidad de vida de las personas 6 , 7 . En la última década, ha surgido evidencia que sugiere una asociación entre las dos condiciones 8 - 10 .…”