Impact of capsule endoscopy in obscure small-bowel bleeding: defining strict diagnostic criteria for a favorable outcome

Viazis, Nikos; Papaxoinis, Kostis; Theodoropoulos, Ioannis; Sgouros, Spiros; Vlachogiannakos, John; Pipis, Prokopis; Markoglou, Costas; Avgerinos, Alec

doi:10.1016/j.gie.2005.06.049

Cited by 54 publications

(37 citation statements)

References 22 publications

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“…Other investigators have suggested that there was no statistically significant difference in diagnostic yield between those patients with occult and those with overt bleeding [12,14,15,[27][28][29][30]. The demonstrably higher yield in overt bleeding in our study probably reflects the larger cohort (n = 159) and is in agreement with the findings of Pennazio et al (n = 100) [15].…”

Section: Discussionsupporting

confidence: 91%

Capsule Endoscopy Changes Patient Management in Routine Clinical Practice

et al. 2007

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Our objective was to evaluate the diagnostic yield and effect of capsule endoscopy on patient management in routine clinical practice. Three hundred examinations were performed (176 females; mean age, 51 years), with a median follow-up of 17 months. Indications included overt bleeding (n=55), anemia (n=104), suspected Crohn's disease (n=68), celiac disease (n=35), suspected functional symptoms (n=23), polyposis (n=5), and miscellaneous (n=10). The overall diagnostic yield was 39%, but it was notably higher in overt bleeders, 66%, compared to 46% in the anemia group (P<0.025), 32% in the suspected Crohn's group (P<0.001), and 17% in the functional group (P<0.001). As a result of capsule endoscopy, management was altered in 26% of patients. This study shows that capsule endoscopy has both a high diagnostic yield and an impact on subsequent patient management. These data further support the role of capsule endoscopy in routine clinical practice.

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Section: Discussionsupporting

confidence: 91%

Capsule Endoscopy Changes Patient Management in Routine Clinical Practice

et al. 2007

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“…Furthermore, the existence of a technique (CE) that offers exploration of the entire small bowel in a simple manner probably allows an earlier diagnosis for less evolved stages of tumors, avoiding many urgent laparotomies. In previous CE studies, a variable tumor incidence of 2% to 7.9% was observed [7,10,11,12,13,17].…”

Section: Discussionmentioning

confidence: 83%

“…Previous studies have proved its high diagnostic yield, which is higher than with other explorations and has a positive impact on the management and evolution of patients [11,17]. In OGIB studies with CE, tumor pathology is the third most frequent finding after vascular and inflammatory pathology.…”

Section: Discussionmentioning

confidence: 99%

Incidence of tumoral pathology according to study using capsule endoscopy for patients with obscure gastrointestinal bleeding

et al. 2007

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“…Since the source of OGIB is frequently located beyond the reach of conventional enteroscopy, diagnostic workup for patients with OGIB had been a matter of dilemma for gastroenterologists until the development of capsule endoscopy (CE) [2] and double (DBE) or single balloon enteroscopy [3]. The clinical advantage of CE has been particularly advocated in patients with OGIB [4], and the diagnostic yield of CE in OGIB has been reported to range from 30 to 80% [5][6][7][8][9][10][11], the value of which is higher than those obtained by push enteroscopy [12,13], smallbowel radiography [13,14], and computed tomography (CT) [15,16]. Based on these findings, CE has been defined as the examination of choice for patients with OGIB after negative EGD and colonoscopy [4,11].…”

Section: Introductionmentioning

confidence: 99%