Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests

Pollack, Ross A.; Brown, Siobhan P.; Rea, Thomas D.; Aufderheide, Tom P.; Barbic, David; Buick, Jason E.; Christenson, James M.; Idris, Ahamed H.; Jasti, Jamie; Kampp, Michael; Kudenchuk, Peter J.; May, Susanne; Muhr, Marc; Nichol, Graham; Ornato, Joseph P.; Sopko, George; Vaillancourt, Christian; Morrison, Laurie J.; Weisfeldt, Myron L.

doi:10.1161/circulationaha.117.030700

Cited by 150 publications

(122 citation statements)

References 40 publications

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“…The use of an AED has been associated with increased survival in Out of Hospital Cardiac Arrest (OHCA) in a large variety of studies were the AED had been used in community programmes and in crowded places such as airports, casino's and airplanes. [1][2][3][4][5][6][7] Only very few data is available about the circumstances and outcomes of resuscitation and the use of AEDs on lifeboats. [8][9][10][11] The aim of this study is to evaluate circumstances, patient outcomes and quality of CPR performed by lifeboat crewmembers.…”

Section: Introductionmentioning

confidence: 99%

Circumstances, outcome and quality of cardiopulmonary resuscitation by lifeboat crews

Seesink

Nieuwenburg

Linden³

et al. 2019

Resuscitation

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Background: Little is known regarding circumstances, outcomes and quality of cardiopulmonary resuscitation (CPR) and the use of automated external defibrillators (AEDs) performed by operational lifeboat crews. Our aim is to evaluate circumstances, outcomes and quality of CPR performed by the Royal Dutch Lifeboat Institution (KNRM) in out-of-hospital cardiac arrest (OHCA). Methods:The internal KNRM database has been used to identify and analyse all OHCA cases between July 2011 and December 2017. A limited set of AED data was available to study the quality of CPR.Results: In 37 patients the lifeboat crew members have performed CPR, of which 29 (78.4%) occurred under hostile conditions. The median response time to arrive at the location was 15 min. In 11 (29.7%) patients return of spontaneous circulation was achieved at any moment during CPR and 3 (8.1%) patients were still alive after one month. The lifeboat AED was used in 12 patients. Their recordings show a high median compression frequency (120, IQR 111-131) and prolonged median interruption periods (pre-analysis pause 11s (IQR 10-13), post-analysis pause 4s (IQR 3-8), pre-shock pause 24s (IQR 19-26), post-shock pause 6s (IQR 6-11), ventilation pause 6s (IQR 4-8) and other pauses 9s (IQR 4-17)).Conclusions: Compared to most out-of-hospital resuscitations, resuscitations by lifeboat crews have a low incidence, occur under difficult circumstances and in a younger population. AED's on lifeboats have not contributed to any of the survivals. Analysis of AED information can be used to study the quality of CPR and provide input for improving future training of lifeboat crews.

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Section: Introductionmentioning

confidence: 99%

Circumstances, outcome and quality of cardiopulmonary resuscitation by lifeboat crews

Seesink

Nieuwenburg

Linden³

et al. 2019

Resuscitation

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“…• Lay rescuers: Bystander CPR has consistently been shown to improve the likelihood of survival from OHCA, which decreases with every minute that CPR and defibrillation are delayed. [14][15][16] Rescuers in the community are unlikely to have access to adequate PPE and, therefore, are at increased risk of exposure to COVID-19 during CPR, compared to healthcare providers with adequate PPE. Rescuers with increasing age and the presence of comorbid conditions, such as heart disease, diabetes, hypertension, and chronic lung disease, 5 are at increased risk of becoming critically ill if infected with SARS-CoV2.…”

Section: Situation-and Setting-specific Considerationsmentioning

confidence: 99%

Interim Guidance for Basic and Advanced Life Support in Children and Neonates With Suspected or Confirmed COVID-19

Topjian¹,

Aziz²,

Kamath‐Rayne³

et al. 2020

Pediatrics

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“…More details were provided, when explicitly reporting the rules for correcting data values, or reporting the range of admissible values and number of records with values outside the range in the Supplement (10). One paper included the computer code used for data cleaning in the Supplement (20), which made the data cleaning potentially reproducible.…”

Section: Data Cleaningmentioning

confidence: 99%

“…Pollack et al adjusted their analysis for potential confounders. "For example, bystander AED shock was more likely to receive bystander CPR, so we adjusted for this covariate in the analysis," acknowledging that obseved differences in survival could not be attributed solely to the type of help recieved by patients (20).…”

mentioning

confidence: 99%

Hidden analyses: A review of current reporting practice and recommendations for more transparent reporting of initial data analyses

Huebner

Vach

Cessie

et al. 2020

Preprint

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Background In the data pipeline from the data collection process to the planned statistical analyses, initial data analysis (IDA) typically takes place between the end of the data collection and do not touch the research questions. A systematic process for IDA and clear reporting of the findings would help to understand the potential shortcomings of a dataset, such as missing values, or subgroups with small sample sizes, or shortcomings in the collection process, and to evaluate the impact of these shortcomings on the research results. A clear reporting of findings is also relevant when making datasets available to other researchers. Initial data analyses can provide valuable insights into the suitability of a data set for a future research study. Our aim was to describe the current practice of reporting of initial data analyses in observational studies in five highly ranked medical journals with focus on data cleaning, screening, and reporting of findings which led to a potential change in the analysis plan. Methods This review was carried out using systematic search strategies with eligibility criteria for articles to be reviewed. A total of 25 papers about observational studies were selected from five medical journals. Each paper was reviewed by two reviewers and IDA statements were further discussed by all authors. The consensus was reported. Results IDA statements were reported in the methods, results, discussion, and supplement of papers. Ten out of 25 papers (40%) included a statement about data cleaning. Data screening statements were included in all articles, and 18 (72%) indicated the methods used to describe them. Item missingness was reported in 11 papers (44%), unit missingness in 15 papers (60%). Eleven papers (44%) mentioned some changes in the analysis plan. Reported changes referred to missing data treatment, unexpected values, population heterogeneity and aspects related to variable distributions or data properties. Conclusion Reporting of initial data analyses were sparse, and statements on IDA were located throughout the research articles. There is a lack of systematic reporting of IDA. We conclude the article with recommendations on how to overcome shortcomings in the current practice of IDA reporting in observational studies.

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Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests

Cited by 150 publications

References 40 publications

Circumstances, outcome and quality of cardiopulmonary resuscitation by lifeboat crews

Circumstances, outcome and quality of cardiopulmonary resuscitation by lifeboat crews

Interim Guidance for Basic and Advanced Life Support in Children and Neonates With Suspected or Confirmed COVID-19

Hidden analyses: A review of current reporting practice and recommendations for more transparent reporting of initial data analyses

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