Impact of binocular integrated visual field defects on healthy related quality of life in glaucoma

Abstract

To investigate the impact of different types of binocular integrated visual field defects on the quality of life in glaucoma. Ninety-six patients with primary glaucoma were divided into 5 groups with 25, 24, 11, 15, and 21 patients according to types of the binocular integrated visual field (BVF) defects. The criteria for BVF grouping included mild visual field defect in binocular eyes, mild visual field defect in 1 eye and moderate or advanced defect in the other, moderate and non-overlapping visual field defect in both eyes, overlapping and moderate visual field defect in binocular eyes, and severe defect in both eyes, respectively. The visual field (VF) evaluation was based on H-P-A visual field grading system. Visual acuity, visual field tests and Glaucoma Quality of Life-15 Questionnaire (GQL-15) were performed for enrolled patients, and binocular visual field results were integrated. The changes and correlations of the Visual field index values and quality of life scores were compared among the 5 groups. The main factors affecting the quality of life in glaucoma were analyzed by multiple regression analysis. The best binocular integrated visual field index (BVFI) and optimal quality of life were observed in group A. The BVFI of group B was better than that of group C or group D, but the peripheral vision glare and dark adaptation were worse. No significant difference was noted between group C and group D in terms of BVFI. However, the glare and dark adaptation in group C were better than that in group D. The BVFI was the lowest and the quality of life was the worst in group E. In all, BVFI and decibels (dB) values were negatively correlated with GQL-15 scores and positively correlated with patients’ quality of life. Binocular integrated visual field accurately reflects the visual function in glaucoma. Higher binocular integrated visual field indices represent a better quality of life for patients with glaucoma. Mild to moderate synchronous or complementary binocular VF defects had a slight effect on the quality of life, while severe and non-compensated VF loss significantly impacts on quality of life in glaucoma patients.

Vision-Related Quality of Life and Associated Factors Among an Adult Population with Glaucoma Attending a Comprehensive Specialized Hospital, Northwest Ethiopia

“…The mean scores of the four GQL-15 subscales, namely, “Central and Near vision”, “Outdoor mobility”, “Peripheral vision” and “Glare and Dark adaptation” were 46.76, 45.61, 44.31 and 51.95 respectively, indicating that, greater difficulties were noted in the glare and dark adaptation domain. This pattern was supported by previous reports of studies conducted in Ethiopia, 13 Nigeria, 23 India, 24 China, 14 , 22 and Australia. 26 The possible justification for such a pattern might be because glare sensitivity is one of the biggest side effects of glaucoma-related fear of light resulting from the intra-ocular pressure rise in the eye.…”

“…The finding was consistent with that of previously conducted in Gondar, Ethiopia, 13 46.3. However, the finding was higher denoting poorer VRQOL, compared to the findings of the previous studies conducted in Nigeria, 24.07, 23 India, 26.0, 24 China; 26.0, 25 28.79, 14 and 31.86, 22 Australia, 30.5, 26 England, 22.09 19 and the Netherlands, 28. 27 These discrepancies may be explained by various factors including variation in the socio-economic and clinical characteristics of the study participants, sampling methods, and inclusion and exclusion criteria used by the studies.…”

“…The patients are at increased risk of various complications secondary to treatments and the disease itself contributing to poor VRQOL. 22 Thus, the present study evaluated the Vision-Related Quality of Life of patients with glaucoma at Felege Hiwot Tertiary Hospital, Northwest Ethiopia.…”

The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial

“…A number of reports on glaucoma patients have described difficulties in performing daily activities and loss of vision-related quality of life [8][9][10][11][12][13][14][15][16]. Loss of binocular visual field (VF) and central best corrected visual acuity (BCVA) have been shown to be major factors leading to reduced quality of life in glaucoma [17][18][19].…”

Socio-Demographic, lifestyle and eye-related factors associated with quality of life Among people with glaucoma in Serbia

“…6 However, there is a gap in studies that take on a comprehensive approach to the VRQoL impairment in glaucoma. Previous studies examined certain aspects that might be associated with VRQoL in glaucoma, such as knowledge about glaucoma 7 and health literacy , 8 psychological factors 9 visual impairment , 10 visual field defects , 11 glaucoma-specific medications 12 and interventions 13,14 or environmental conditions. 15 Other studies examined multiple factors affecting VRQoL in patient with glaucoma , [16][17][18][19] however, they did not include an analysis of interventions or glaucoma subtype.…”