Impact of Baseline Right Bundle Branch Block on Outcomes After Pulmonary Vein Isolation in Patients With Atrial Fibrillation

Association between complete right bundle branch block and atrial fibrillation development

“…In addition, a recent study evaluated the impact of baseline CRBBB on outcomes after pulmonary vein isolation in patients with AF and found that CRBBB was an independent predictor of AF recurrence after pulmonary vein isolation. (Yano et al, 2021 ) In the present study, the univariate and multivariate analyses showed that CRBBB was independently associated with AF development. Several mechanisms may account for the relationship between CRBBB and AF development.…”

“…(Bussink et al, 2013 ) Furthermore, the prevalence of CRBBB may be higher in patients with hypertension, diabetes mellitus, and AF. (Miller et al, 2008 ; Movahed, 2007 ; Yano et al, 2021 ) In a recent large community‐based cohort study of 90,022 individuals aged 40–79 years who participated in annual community‐based health check‐ups, the prevalence of CRBBB was 1.5%. (Nakazawa et al, 2021 ) In our study, the prevalence of CRBBB was also 1.5%, but our study population included patients aged <40 years, all of whom were hospitalized at the Heart Center of Henan Provincial People's Hospital and the majority of whom had cardiovascular diseases.…”

“…This is supported by the findings of a recent study, which showed that with repeated AF ablation, the incidence of nonpulmonary vein AF triggers (confirmed firing to AF), especially in the superior vena cava, was significantly higher in patients with CRBBB than in those without CRBBB. (Yano et al, 2021 ) Third, because the prevalence of CRBBB increases with age, CRBBB may be a marker of a slowly progressing degenerative disease, such as Purkinje system fibrosis or myocardial fibrosis. (Koshiyama et al 2021 ) Fibrosis of the atrial tissue predisposes an individual to AF development.…”

“…(Bussink et al, 2013 ; Cinca et al, 2013 ; Kleemann et al, 2008 ; Manzano et al, 2011 ; McCullough et al, 2005 ; Nakazawa et al, 2021 ; Widimsky et al, 2012 ; Wong et al, 2006 ) Furthermore, a recent study showed that CRBBB is an independent predictor of AF recurrence after pulmonary vein isolation. (Yano et al, 2021 ) In patients with CRBBB who have undergone AF ablation, most of the pathogenic factors for AF exist before ablation. It is reasonable to hypothesize that CRBBB is also associated with AF development.…”

Association of right bundle branch block or intraventricular conduction delay with recurrence of atrial fibrillation after catheter ablation

“…AF frequently occurs in conjunction with a myriad of conduction abnormalities (Thiyagarajah et al, 2018), and the combination of AF and BBB portends greater recurrence of AF after catheter ablation. Several studies found that AF with BBB was associated with a higher recurrence rate of AF after catheter ablation (Mujovic et al, 2017; Peigh et al, 2020; Thiyagarajah et al, 2018; Yano et al, 2021). A recent study by Yano et al (2021) showed that baseline RBBB had a significantly greater risk of AF recurrence after catheter ablation than those without RBBB (Yano et al, 2021).…”