Impact of Atrial Fibrillation on Hospitalization Outcomes of Heart Failure in Patients ≥ 60 Years with Implantable Cardioverter Defibrillator

Abugroun, Ashraf; Elawad, Ahmed; Okoh, Alexis K.; Abdel-Rahman, Manar E.; Ayinde, Hakeem; Volgman, Annabelle Santos

doi:10.1016/j.amjcard.2021.04.016

Cited by 1 publication

(2 citation statements)

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“…However, the 12‐month freedom from the first occurrence of ICD therapy (90.5%), and freedom from the first occurrence of ICD shock (94.8%) were comparable to the results of published RCTs 7,8,17 . Numerous studies and meta‐analyses revealed that ICD patients with SVA were linked to greater appropriate, inappropriate ICD shock and overall mortality 1,13,18–20 . Unfavorable outcomes in SVA patients are typically caused by a combination of multiple factors, including a progression of heart failure, thromboembolic events, and adverse effects from antiarrhythmic medication use.…”

Section: Discussionsupporting

confidence: 58%

“…7,8,17 Numerous studies and meta-analyses revealed that ICD patients with SVA were linked to greater appropriate, inappropriate ICD shock and overall mortality. 1,13,[18][19][20] ventricular tachycardia. Similar to individuals with SVA, there were no appreciable reductions in mortality rates in those without SVA after using guideline concordance programming.…”

Section: Discussionmentioning

confidence: 99%

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The impact of supraventricular arrhythmias on the outcomes of guideline‐compliant implantable cardioverter defibrillator programming

Teerawongsakul,

Ananwattanasuk,

Chokesuwattanaskul

et al. 2024

Cardiovasc electrophysiol

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IntroductionSeveral implantable cardioverter defibrillators (ICD) programming strategies are applied to minimize ICD therapy, especially unnecessary therapies from supraventricular arrhythmias (SVA). However, it remains unknown whether these optimal programming recommendations only benefit those with SVAs or have any detrimental effects from delayed therapy on those without SVAs. This study aims to assess the impact of SVA on the outcomes of ICD programming based on 2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement and 2019 focused update on optimal ICD programming and testing guidelines.MethodsConsecutive patients who underwent ICD insertion for primary prevention were classified into four groups based on SVA status and ICD programming: (1) guideline‐concordant group (GC) with SVA, (2) GC without SVA, (3) nonguideline concordant group (NGC) with SVA, and (4) NGC without SVA. Cox proportional hazard models were analyzed for freedom from ICD therapies, shock, and mortality.ResultsSeven hundred and seventy‐two patients (median age, 64 years) were enrolled. ICD therapies were the most frequent in NGC with SVA (24.0%), followed by NGC without SVA (19.9%), GC without SVA (11.6%), and GC with SVA (8.1%). Guideline concordant programming was associated with 68% ICD therapy reduction (HR 0.32, p = .007) and 67% ICD shock reduction (HR 0.33, p = .030) in SVA patients and 44% ICD therapy reduction in those without SVA (HR 0.56, p = .030).ConclusionProgramming ICDs in primary prevention patients based on current guidelines reduces therapy burden without increasing mortality in both SVA and non‐SVA patients. A greater magnitude of reduced ICD therapy was found in those with supraventricular arrhythmias.

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Section: Discussionsupporting

confidence: 58%