Impact of Antidepressant Use on Gastric Bypass Surgery Patients’ Weight Loss and Health-Related Quality-of-Life Outcomes

Characterization of the Improvement in Depressive Symptoms Following Bariatric Surgery

“…Therefore, whilst antidepressant therapy of bariatric surgical patients may be of clinical importance, it appeared to have a slight impact on improvement in depressive symptomology in the current study and had no impact on %EWL at follow-up. The finding that baseline use of antidepressant therapy had a modest impact on weight loss outcomes supports that reported after gastric bypass [55].…”

Antidepressant Drug Therapy Does Not Affect Weight Loss One Year after Gastric Bypass Surgery

“…It could be hypothesized that a patient who is successfully treated for their pre-existing disease should have the same outcome as an individual without the same diagnoses. This hypothesis is supported by the findings of the present study and those from Love et al [11].…”

“…Interestingly, the use of antidepressant drug medication has seldom been reported in the majority of studies. Love et al [11] reported data from 116 gastric bypass patients who were divided into those taking antidepressants versus those who were not. The type of antidepressant was not reported.…”

Preoperative Predictors of Weight Loss Following Bariatric Surgery: Systematic Review

“…Four of 19 studies reported a negative association between depression and postoperative weight loss [45,51,108,114], 14 reported no association [10,15,23,25,48,51,60,62,82,91,95,[115][116][117], and one reported a positive association [47] (n=5,209 patients). Follow-up time was relatively consistent among the studies, with studies that had a negative association having 12-36-month follow-up, the positive association study having 12-month follow-up, and the no association studies having 6-60-month followup (two studies with 6-month follow-up, six studies with 12-month follow-up, and the remainder with >12-month follow-up).…”