Impact of anesthesia for cancer surgery: Continuing Professional Development

Platelet-to-Lymphocyte Ratio and Use of NSAIDs during the Perioperative Period as Prognostic Indicators in Patients with NSCLC Undergoing Surgery

“…3,4 Current risk-stratification characteristics used in patients with NSCLC are associated with surgical staging and include tumor size, invasion to adjacent organs, nodal status, and presence of metastasis. Some clinically available inflammatory biomarkers have been identified to improve and guide therapy in patients with cancer, particularly those with NSCLC.…”

Effects of preemptive analgesia with flurbiprofen ester on lymphocytes and natural killer cells in patients undergoing esophagectomy: A randomized controlled pilot study

“…A surgical trauma‐induced stress response can lead to the inhibition of cellular immunity in patients . With the development of minimally invasive endoscopic techniques, thoracoscopic esophageal resection results in less trauma, fewer complications, and better long‐term effects .…”

“…The primary local treatment of many cancers is surgery. In the context of cancer, the operative stress response and the opioid commonly used in clinical anesthesia can inhibit the immune function . This aggravated immune dysfunction may cause postoperative infection and sepsis.…”

“…More effective intraoperative analgesia and reduced opioid use can improve a patient's immune function, reduce the incidence of infection, and promote postoperative recovery . Non‐steroidal anti‐inflammatory analgesia could be a solution to avoid the use of opioids.…”

“…In the context of cancer, the operative stress response and the opioid commonly used in clinical anesthesia can inhibit the immune function. [4][5][6][7][8] This aggravated immune dysfunction may cause postoperative infection and sepsis. Therefore, minimizing the impact of surgical and medical procedures on a patient's immune function would improve prognosis.…”