In this paper radio channel characterisation and level system modeling for ultra wideband (UWB) in vivo communication is presented at different distances and angle between the the implant and the on-body node. Path loss is calculated for different scenarios and time delay analysis is performed. In addition, UWB-OFDM (orthogonal frequency division multiplexing) based system modeling is used to calculate the bit error rate (BER) performance. Result shows that BER remains less then 1 −3 for almost all cases up to 40 mm spacing between the implant and on-body node, when / is above 6 dB. Index Terms-in body/in-vivo, ultra wideband, body area network, system modeling.