Impact of an antimicrobial resistance control program: pre- and post-training antibiotic use in children with typhoid fever

Rachmah, Elfrida A.; Rochmanti, Maftuchah; Puspitasari, Dwiyanti

doi:10.14238/pi56.4.2016.205-10

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…Antimicrobial stewardship efforts are urgently needed, and smart strategies for AMR surveillance can contribute to such efforts and inform clinicians as well as policy makers. Studies in Indonesia and China have shown that educational training on antimicrobial stewardship for prescribers and patients alike can lead to a reduction in antibiotic prescriptions (35, 36).…”

Section: Discussionmentioning

confidence: 99%

Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling

Ginting

Sugianli

Bijl

et al. 2019

American Journal of Epidemiology

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Global surveillance of antimicrobial resistance (AMR) is a key component of the 68th World Health Assembly Global Action Plan on AMR. Laboratory-based surveillance is inherently biased and lacks local relevance due to aggregation of data. We assessed the feasibility, sensitivity, and affordability of a population-based AMR survey using lot quality assurance sampling (LQAS), which classifies a population as having a high or low prevalence of AMR based on a priori defined criteria. Three studies were carried out in Medan and Bandung, Indonesia, between April 2014 and June 2017. LQAS classifications for 15 antibiotics were compared with AMR estimates from a conventional population-based survey, with an assessment of the cost of a single LQAS classification using microcosting methodology, among patients suspected of urinary tract infection at 11 sites in Indonesia. The sensitivity of LQAS was above 98%. The approach detected local variation in the prevalence of AMR across sites. Time to reach LQAS results ranged from 47 to 138 days. The average cost of an LQAS classification in a single facility was US$466. The findings indicate that LQAS-based AMR survey is a feasible, sensitive, and affordable strategy for population-based AMR surveys, providing essential data to inform local empirical treatment guidelines and antimicrobial stewardship efforts.

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Section: Discussionmentioning

confidence: 99%

Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling

Ginting

Sugianli

Bijl

et al. 2019

American Journal of Epidemiology

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“…The Gyssens algorithm is a qualitative measurement to assess antibiotic usage and has been widely used in worldwide studies. The Gyssens algorithm will show the rationality of antibiotic usage based on grouping of 0-VI categories 2,13 . A chi-square test was used to identify the impact of appropriate antibiotic use on the 30-days readmission and mortality.…”

Section: Methodsmentioning

confidence: 99%

“…This unabating phenomenon increasingly becomes a problem in public health issues. Antibiotic resistance will rapidly increase along with inappropriate antibiotic use [1][2][3] . As methicillin was widely used in the 1960s, Staphylococcus aureus soon becomes resistant to the drug, treatment decision for MRSA infection can be challenging due to a change in its Penicillin Binding Protein (PBP) so that it is resistant to beta-lactam class antibiotics [4][5][6] .…”

Section: Introductionmentioning

confidence: 99%

Appropriate Antibiotic Use for Community-Acquired Pneumonia in Inpatient Settings and Its Impact on 30-days Readmission and Mortality Rate

2021

IJFMT

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Background: Community-Acquired Pneumonia (CAP) is a lower respiratory tract infection with bacteria as the most frequent causative agent. Therapy for pneumonia includes appropriate antibiotic usage. Inappropriate antibiotic use supposedly increase 30-days readmission and mortality rate.Objective: To evaluate the antibiotic use and the impact of appropriate antibiotic use on the 30-days readmission and mortality of CAP patients in inpatient non-ICU settings. Method:A cross-sectional, analytic study was conducted. We collected data from Universitas Airlangga hospital's medical record to obtain the details of antibiotic usage. Result were evaluated using the Gyssens algorithm. A chi-square test was used to identify the impact of appropriate antibiotic use on the 30-days readmission and mortality.Result: A total of 90 patients with CAP fulfilled the inclusion criteria. One gram of ceftriaxone IV was the most prescribed antibiotic for therapy of CAP. The amount of appropriate antibiotic use is 85.6%. Five patients (5.6%) went through the 30-days readmission. There was no death reported. The statistical test between antibiotic use and 30-days readmission obtained p value=0.894 (p>0.05). Conclusion:There was no significant impact of appropriate antibiotic use on the 30-days readmission rate and the mortality rate could not be assessed.

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Impact of an antimicrobial resistance control program: pre- and post-training antibiotic use in children with typhoid fever

Abstract: Background Antibiotics are the main treatment for typhoid fever. In-

Cited by 2 publications

References 9 publications

Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling

Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling

Appropriate Antibiotic Use for Community-Acquired Pneumonia in Inpatient Settings and Its Impact on 30-days Readmission and Mortality Rate

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