Impact of Age and Basic Heart Rate on Heart Rate Turbulence in Healthy Persons

Schwab, Jörg O.; Eichner, Gerrit; Шлевков, Н. Б.; Schrickel, Jan W.; Yang, Alexander; Balta, Osman; Lewalter, Thorsten; Lüderitz, Berndt

doi:10.1111/j.1540-8159.2005.00042.x

Cited by 27 publications

(24 citation statements)

References 12 publications

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“…Our data are not compliant with those of Schwab et al (7), who found significant correlations among age, heart rate, and TO in healthy persons. In their study, TO increased with increasing age and increasing heart rate, otherwise the values of TO become more positive.…”

contrasting

confidence: 55%

“…Mean RR was chosen to avoid potential errors associated with counting of HR before VPB. Recently, Schwab et al (7) found correlation between TS and RR intervals preceding VPB in healthy adult persons, although their statistical strength were weaker than in our study. They showed that TS slope decreased with increasing basic heart rate preceding VPB.…”

contrasting

confidence: 51%

“…A few studies demonstrate that in healthy subjects increasing age is associated with a decrease of HRT slope (6,7), likewise an increase in heart rate is relevant to TO decrease. However, there is a lack of information about heart rate turbulence behavior after VPB and the potential influence of age and pubertal status on healthy subjects within first two decades of life.…”

mentioning

confidence: 99%

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Heart Rate Turbulence in Children—Age and Heart Rate Relationships

Kowalewski¹,

Adam

Bochen

et al. 2007

Pediatr Res

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Heart rate turbulence (HRT) is a chronotropic response of the sinus heart rhythm to ventricular premature beat (VPB). Children show decreasing heart rate together with the maturation of the autonomic nervous system. The aim of the research was to assess the relationship between HRT parameters, age, and heart rate and time domain heart rate variability (HRV) parameters in healthy children. Twenty-four-hour ECG Holter recording was performed on 398 healthy children. The mean RR interval preceding VPB, number of VPBs, and HRT parameters-turbulence onset (TO) and turbulence slope (TS)-were determined. We observed significant correlation among TS and mean RR and age. Children with prepubertal status have lower values of TS compared with those during puberty. According to given quartiles, upper for TO was Ն-0.8%, lower for TS was Յ4.56 ms/RR, 13 patients (3%) obtained abnormal both TO and TS. The correlations between HRT and HRV parameters were observed among the youngest children. Age and heart rate preceding VPB have no effect on HRT onset in children, whereas HRT slope is highly dependent on these variables. Our results support hypothesis that in older children HRT is dependent on autonomic tone and also determined by other intrinsic modulators. T he term "heart rate turbulence" (HRT) was first used by Schmidt et al. (1) and refers to changes in the sinus heart rhythm after ventricular premature beat (VPB). The response consists of a short phase of early heart rate acceleration followed by heart rate deceleration. HRT can be quantified by two parameters, turbulence onset (TO) and turbulence slope (TS), which are strong and independent markers of a sudden cardiac death risk in various patients' cohorts (1,2). The underlying mechanism of described parameters is connected with compensatory activation of baroreceptor reflex triggered by a decreased stroke volume following a VPB. The HRT response is believed to be under strong dependence on parasympathetic activity and heart rate preceding VPB (3). Recent studies have shown that HRT phenomenon can be used as an alternative measure of baroreflex sensitivity (4,5).A few studies demonstrate that in healthy subjects increasing age is associated with a decrease of HRT slope (6,7), likewise an increase in heart rate is relevant to TO decrease. However, there is a lack of information about heart rate turbulence behavior after VPB and the potential influence of age and pubertal status on healthy subjects within first two decades of life. Changes in basic heart rhythm during child's development are influenced by breathing frequency, sleeping periods and maturation of sympathetic and parasympathetic systems (8). We hypothesized that in such population age heart rhythm may significantly influence the heart rate turbulence parameters.The aim of this study was to determine the correlation among the HRT parameters, age, heart rate, heart rate variability (HRV) parameters and pubertal status in healthy children. MATERIALSAll the participants had a documented history of vent...

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confidence: 55%

contrasting

confidence: 51%

mentioning

confidence: 99%

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Heart Rate Turbulence in Children—Age and Heart Rate Relationships

Kowalewski¹,

Adam

Bochen

et al. 2007

Pediatr Res

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“…Значения TO были <0% во всех случаях. Половых различий ТРС не было выявлено [137,138], однако с возрастом параметры ТРС редуцируются [139].…”

Section: новые технологииunclassified

National Russian Guidelines on Application of the Methods of Holter Monitoring in Clinical Practice

Макаров¹,

Комолятова²,

Куприянова³

et al. 2014

Russ J Cardiol

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“…For example, compared to healthy control patients, patients with congestive heart failure have significantly depressed HRT indexes [39]. Also, increasing age is associated with a decrease in the HRT index [60]. It is reported in [67] that TO is significantly less According to the discussion above, we use PLFME for the cardiac signal.…”

Section: Application To Human Heartbeat Interval Time Seriesmentioning

confidence: 99%

Filter-based multiscale entropy analysis of complex physiological time series

Zhao

2013

Phys. Rev. E

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Zhao, Liang, "Filter-based multiscale entropy analysis of complex physiological time series" (2013). Dissertations -ALL. Paper 3. ABSTRACTThe multiscale entropy (MSE) has been widely and successfully used in analyzing the complexity of physiologic time series. In this thesis, we re-interpret the averaging process in MSE as filtering a time series by a filter of a piecewise constant type. From this viewpoint, we introduce the filter-based multiscale entropy (FME) which filters a time series by filters to generate its multiple frequency components and then compute the blockwise entropy of the resulting components. By choosing filters adapted to the feature of a given time series, FME is able to better capture its multiscale information and to provide more flexibility for studying its complexity. Motivated by the heart rate turbulence theory which suggests that the human heartbeat interval time series (HHITS) can be described in piecewise linear patterns, we propose the piecewise linear filter multiscale entropy (PLFME) for the complexity analysis of the time series. Numerical results from PLFME are more robust to data of various lengths than those from MSE. We then propose wavelet packet transform entropy (WPTE) analysis. We apply WPTE analysis to HHITS using lower and higher piecewise linear filters. Numerical results show that WPTE using piecewise linear filters gives us the highest classification rates discriminating different cardiac systems among other multiscale entropy analysis. At the end, we discuss the application of FME on discrete time series. We introduce an 'eliminating' algorithm to examine and compare the complexity of coding and noncoding DNA sequences.

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Impact of Age and Basic Heart Rate on Heart Rate Turbulence in Healthy Persons

Cited by 27 publications

References 12 publications

Heart Rate Turbulence in Children—Age and Heart Rate Relationships

Heart Rate Turbulence in Children—Age and Heart Rate Relationships

National Russian Guidelines on Application of the Methods of Holter Monitoring in Clinical Practice

Filter-based multiscale entropy analysis of complex physiological time series

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